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Homocysteine

Biochemical component reference page from the Everyone Healthy database.

Full information

Homocysteine

ID 574

Homocysteine is an amino acid that is produced by the body.

Amino acids are the building blocks of proteins.

Homocysteine cannot be obtained directly from any foods.

Foods containing methionine are transformed into homocysteine in the bloodstream.

The body them converts the homocysteine to cysteine.

The body uses vitamin B6 to facilliate the reaction of homocysteine to cysteine.

Homocysteine can be converted back to methionine using vitamin B12 related enzymes

Cysteine is a important amino aicd and is involved in:

                                                                                               1. The way proteins are folded

                                                                                               2. Maintains the shape of proteins

                                                                                               3. How proteins link to each other

                                                                                               4.  A Source of sulfide

                                                                                               5.  Anti oxidations

Elevated levels of homocysteine levesl have been associated with heart attack, stroke, blood clot formation and Alzheimers Disease.

Plasma concentrations of homocsyteine vary but intracellular concentrations of homocysteine are normally maintained within a very narrow range.


References

1. https://www.mja.com.au/journal/2004/181/6/clinical-usefulness-plasma-homocysteine-vascular-disease

Reference ranges and concentrations

2

Reference ranges come from the existing EH diagnostic-test range tables. Ranges can differ between laboratories, methods, age groups and clinical situations.

Diagnostic test / concentrationReference rangeUnitAgeGenderCategory / test group
Homocysteine Concentration (HCY, Blood)4 – 15µmol/LAllFemaleBlood Studies / Blood Enzymes
Homocysteine Concentration (HCY, Blood)7 – 16µmol/LAllMaleBlood Studies / Blood Enzymes

Tip: scroll sideways on small screens to see all columns. Ranges are educational only and must be interpreted by a qualified clinician.

Conditions linked to this marker

23

This shows where the EH database links this marker as increased, decreased or associated with conditions.

Diagnostic tests linked to this marker

1