Everyone Healthy Library
ABO Hemolytic Disease of the Newborn
Condition / disease reference page from the Everyone Healthy database.
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Connected health information
Explore this condition in a clear order
Linked signs and symptoms
8Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
0No linked drugs are listed yet.
Treatments, therapies and supportive options
2Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Medical therapy
1Linked diagnostic tests and investigations
9These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Amniotic Fluid Bilirubin Concentration
- Bilirubin Concentration (Neonates, Neonatal Bilirubin)
- Coagulation Factor Assay (Blood Clotting Factors)
- Erythrocyte Fragility Test (Osmotic Fragility, OF)
- Fecal Urobilinogen Concentration
- Free Erythrocyte Protoporphyrin (FEP) Concentration
- Glucose 6 Phosphate Dehydrogenase (G6PD) Concentration
- Protein Electrophoresis (Blood, Serum Protein)
- Red Blood Cell Distribution Width (RDW) Test
Biological markers/agents
11This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
7- Amniotic Fluid BilirubinReference range exampleAdult ( > 16y), Female: 0–0.2 mg/dLLinked diagnostic testsAmniotic Fluid Bilirubin Concentration
- BilirubinReference range exampleBirth - 2wks: 1–10 mg/dL; 0.3–1Linked diagnostic testsBilirubin Concentration (Neonates, Neonatal Bilirubin)
- Free Erythrocyte Protoporphyrin (FEP)Reference range exampleAll: 16–37 µg/dLLinked diagnostic testsFree Erythrocyte Protoporphyrin (FEP) Concentration
- Percentage NaCl at which Hemolysis beginsReference range exampleAll: 0.5–0.6 %Linked diagnostic testsErythrocyte Fragility Test (Osmotic Fragility, OF)
- Percentage NaCl at which Hemolysis is completeReference range exampleAll: 0.3–0.35 %Linked diagnostic testsErythrocyte Fragility Test (Osmotic Fragility, OF)
- Red Blood Distribution Width (RDW)Reference range exampleAll: 11–14.5 %Linked diagnostic testsRed Blood Cell Distribution Width (RDW) Test
- Urobilinogen (Stools)Reference range exampleAll: 50–300 mg/24hrsLinked diagnostic testsFecal Urobilinogen Concentration
Often decreased
4- Alpha-1-Globulin (Blood, Serum)Reference range exampleAll: 0.1–0.3 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Alpha-2-Globulin (Blood, Serum)Reference range exampleAll: 0.6–1 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Factor VII (Stable Factor, Proconvertin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 65–140 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Glucose 6 Phosphate Dehydrogenase (G6PD)Reference range exampleAdult ( > 16y): 10.1–18.5 U/gHb; Birth - 2wks: 12–23 U/gHbLinked diagnostic testsGlucose 6 Phosphate Dehydrogenase (G6PD) Concentration
Introduction / full article
ABO Hemolytic Disease of the Newborn
Summary References
Treatments:
1. http://www.obgyn.net/english/pubs/features/presentations/panda13/ABO-Rh.ppt
2. Wang, M, Hays T, Ambruso, DR, Silliman CC, Dickey WC. Hemolytic Disease of the Newborn Caused by a High Titer Anti-Group B IgG From a Group A Mother. Pediatric Blood & Cancer 2005;45(6): 861-862
3. Jeon H, Calhoun B, Pothiawala M, Herschel M, Baron BW. Significant ABO Hemolytic Disease of the Newborn in a Group B Infant with a Group A2 Mother. Immunohematology 2000; 16(3):105-8.
4. Haque KM, Rahman M. An Unusual Case of ABO-Haemolytic Disease of the Newborn. Bangladesh Medical Research Council Bulletin 2000; 26(2): 61-4.
5. http://www.nlm.nih.gov/medlineplus/ency/article/001298.htm
6. http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=rbcantigen&part=ch4
7. http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/hrnewborn/hdn.html