Everyone Healthy Library
Complex Regional Pain Syndrome
Also Known As: Reflex Neurovascular Dystrophy; Reflex Sympathetic Dystrophy Syndrome (RSD)
Condition / disease reference page from the Everyone Healthy database.
Connected health information
Explore this condition in a clear order
Linked signs and symptoms
13Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
5Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
28Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Surgery
2Medical therapy
5- NeuromodulationWeakly in Favour(Low Evidence)
- Spinal Cord Stimulation (SCS)Weakly in Favour(Low Evidence)
- SympathectomyWeakly in Favour(Low Evidence)
- Transcutaneous Electrical Nerve Stimulation (TENS)Weakly in Favour(Low Evidence)
- Transcutaneous Neuromuscular Electrical StimulationNo Recommendation(Low Evidence)
Lifestyle changes
2Behavioural changes
2Counselling and support
2Alternative and complementary therapies
9- Acupuncture
- Black Cohosh Plant (Actaea racemosa)No Recommendation(Moderate Evidence)
- Cannabis (Marijuana)Weakly in Favour(Low Evidence)
- Chaparral (Larrea Tridentata Coville)Strongly Against(Low Evidence)
- OsteopathyNo Recommendation(Low Evidence)
- Physical Therapy
- Polarity TherapyNo Recommendation(Low Evidence)
- Qigong
- ReflexologyWeakly in Favour(Low Evidence)
Alternative medicine
1Alternative therapies
1Linked diagnostic tests and investigations
11These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
Biological and test markers
2This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
1Often decreased
1Other associated markers
0No markers in this group.
Introduction / full article
Complex Regional Pain Syndrome
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Cannabis (Marijuana, weed, hemp) [1, 5, 6, 7, 8, 9, 10, 11, 12, 13]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: Weakly in favor (Evidence shows that smoking or ingesting cannabis may help in relieving symptoms of pain, although some studies have yielded mixed results)
Grade of Evidence: Low quality of evidence
Chaparral (Larrea Tridentata Coville [1, 2, 3, 4]:
Please note, this herb is HIGHLY TOXIC, and has been reported to cause severe and permanent liver disease which can be fatal.
Recommendation: Strongly against (Existing evidence shows that Chaparral is not an effective treatment for complex regional pain syndrome. In addition, this herb is highly toxic and potentially life threatening.)
Grade of Evidence: Low quality of evidence
Black Cohosh (cimicifuga Racemosa):
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (Available evidence does not support claims that Black Cohosh helps to treat symptoms of pain in any way. Studies have yielded mixed results)
Grade of Evidence: Moderate quality of evidence
Transcutaneous Electrical Neuromuscular Stimulation:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (There is not enough evidence supporting the role of TENS in chronic pain therapy)
Grade of Evidence: Low quality of evidence
Reflexology:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: Weakly in favor (A conrolled study showed that Reflexology may help some people with chronic pain for a maximum of three hours, but shows no effect after that)
Grade of Evidence: Low quality of evidence
Polarity Therapy:
Please note, this management does NOT treat the condition itself. It may mildly help with the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (available research does not show that Polarity Therapy might help reduce pain)
Grade of Evidence: Low quality of evidence
Osteopathy:
Please note, this management does NOT treat the condition itself. It may mildly help with the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (Available scientific evidence does not support Osteopathy as helpful alone in chronic pain)
Grade of Evidence: Low quality of evidence
Low-Level Laser Therapy:
Recommendation: No recommendation (There have been ambiguous results on the few studies done investigating the effect of laser therapy on pain)
Grade of Evidence: Very low quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://www.hc-sc.gc.ca/ahc-asc/media/advisories-avis/_2005/2005_135-eng.php
3. Edible and Medicinal Plants of the West, Gregory L. Tilford, ISBN 0-87842-359-1
4. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/chaparral
5. http://www.nlm.nih.gov/medlineplus/marijuana.html
6. http://nccam.nih.gov/research/extramural/awards/2004/
7. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/marijuana
8. http://www.nationalmssociety.org/about-multiple-sclerosis/what-we-know-about-ms/treatments/complementary--alternative-medicine/marijuana/index.aspx
9. http://www.ncbi.nlm.nih.gov/pubmed/16957511
10. http://www.ncbi.nlm.nih.gov/pubmed/12965981
11. http://www.ncbi.nlm.nih.gov/pubmed/17589370
12. http://mct.aacrjournals.org/content/6/11/2921.long
13. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562334/?tool=pmcentrez