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Factor V Resistance To Activated Protein C
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Introduction / full article
Factor V Resistance To Activated Protein C
Factor V Resistance To Activated Protein C
Activated Protein C (APC) inactivates Factor V, which is a protein that is part of the system of coagulation, or the process in which blood clots are formed. A certain mutation of Factor V, called Factor V Leiden, is resistant to APC. This increases the risk of blood clot formation. Venous thrombosis, which is the term for a blood clot formed inside a vein, is a condition caused by Factor V resistance to APC. Symptoms include swelling, change in skin colour, and unusual warmth felt on the affected area. When left untreated, Factor V Resistance to APC can lead to pulmonary embolism. Pulmonary embolism is a condition which affects one of the major arteries of the lung. Factor V Resistance to Activated Protein C can be both genetic and acquired.