Everyone Healthy Library
Gastrointestinal Stromal Tumors
Also Known As: GIST
Condition / disease reference page from the Everyone Healthy database.
Connected health information
Explore this condition in a clear order
Condition overview
Attributes
Commonalityis rare
Commonalityis 15/1000000
Incidenceis approximately 1 in 833,333 people
Linked signs and symptoms
8Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
1Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
6Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Linked diagnostic tests and investigations
14These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Alpha-1 Antitrypsin (AAT) Concentration
- Biopsy of Intestines
- Blood Tests
- Cerebrospinal Fluid Albumin Concentration
- Cerebrospinal Fluid Protein Concentration
- Cerebrospinal Fluid Protein Electrophoresis
- Cerebrospinal Fluid White Cell Differential
- Computerized Tomography (CT) Scan
- Fecal Occult Blood Test
- Fibrin Monomers Test
- Plasminogen Activity
- Platelet Count
- Thyroxine (Total T4) Concentration
- Triiodothyronine (Total T3) Concentration
Biological and test markers
10This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
7- Albumin (Cerebrospinal Fluid, CSF)Reference range exampleAll: 10–35 mg/dL; All: 56–76 %Linked diagnostic tests2Cerebrospinal Fluid Albumin Concentration, Cerebrospinal Fluid Protein Electrophoresis
- Alpha-1 Antintrypsin (AAT)Reference range exampleAdult ( > 16y): 90–215 mg/dLLinked diagnostic tests1Alpha-1 Antitrypsin (AAT) Concentration
- Cerebrospinal Fluid Neutrophil DifferentialReference range exampleAll: 0–5 %Linked diagnostic tests1Cerebrospinal Fluid White Cell Differential
- Cerebrospinal Fluid Total ProteinReference range exampleAdult ( > 16y): 15–45 mg/dL; Child (< 10y): 15–70 mg/dLLinked diagnostic tests1Cerebrospinal Fluid Protein Concentration
- Fecal BloodReference range exampleAll: 0–2 mLLinked diagnostic tests1Fecal Occult Blood Test
- Fibrin MonomersReference range example0–10,000 µg/LLinked diagnostic tests1Fibrin Monomers Test
- PlateletsReference range exampleChild (0 - 16y): 150–450 109/L; Adult ( > 16y): 135–380 109/LLinked diagnostic tests1Platelet Count
Often decreased
3- PlasminogenReference range exampleAdult ( > 16y), Female: 65–153 %; Adult ( > 16y), Male: 70–120 %Linked diagnostic tests1Plasminogen Activity
- Thyroxine (Total T4)Reference range exampleAdult ( > 16y), Female: 6–12 µg/dL; Adult ( > 16y), Male: 5–12 µg/dLLinked diagnostic tests1Thyroxine (Total T4) Concentration
- Triiodothyronine (Total T3)Reference range exampleInfant (0 - 1y): 1.1–2.43 ng/mL; Adult ( > 16y): 1–2.1 ng/mLLinked diagnostic tests1Triiodothyronine (Total T3) Concentration
Other associated markers
0No markers in this group.
Introduction / full article
Gastrointestinal Stromal Tumors
Gastrointestinal stromal tumor
Gastrointestinal stromal tumor is the term used for tumors located in the gastrointestinal tract. These tumors manifest from the mutation of a gene called CKIT. Some cases of gastrointestinal stromal tumor are a side effect of abdominal radiation therapy. Most gastrointestinal stromal tumors develop in the stomach and usually affect people over the age of 50. Symptoms may vary depending on the location and the level of development of the tumor. Symptoms include bleeding and dyspepsia. Endoscopy is done to diagnose the presence of gastrointestinal stromal tumor. Surgery is required to remove the tumors.
Summary References
Treatments:
1. http://www.surgjournal.com/article/S0039-6060%2803%2900314-3/abstract
2. Nguyen SQ, Divino CM, Wang JL, Dikman SH (May 2006). "Laparoscopic management of gastrointestinal stromal tumors". Surg Endosc 20 (5): 713–6. doi:10.1007/s00464-005-0435-
3. "News: Genetic Variations in GI Tumors Determine Which Medications Are Efficacious.". Genetic Engineering & Biotechnology News. 13 Nov 2008. http://www.genengnews.com/news/bnitem.aspx?name=45436906&source=genwire.
4. http://www.merck.com/mmpe/sec02/ch021/ch021e.html?qt=Gastrointestinal%20Stromal%20Tumors&alt=sh