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Granuloma Annulare

Condition / disease reference page from the Everyone Healthy database.

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Condition overview

Attributes

Commonalityis rare

Linked signs and symptoms

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No related signs or symptoms are listed yet.

Linked drugs / medications

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Treatments, therapies and supportive options

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Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.

No linked treatment or supportive options are listed yet.

Linked diagnostic tests and investigations

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These are pulled from both EH diagnostic-test link tables, including the older large test-link table.

Biological and test markers

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This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.

Often decreased

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No markers in this group.

Other associated markers

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Introduction / full article

Granuloma Annulare

ID 821

Granuloma annulare

Granuloma annulare is a chronic skin disease consisting of a rash with reddish bumps arranged in a circle or ring. Granuloma annulare is different from warts, and cryotherapy treatment will not work. It most often affects children, young and older adults and it is slightly more common in females (60/40 ratio).

Causes

The condition is usually seen in otherwise healthy people. Occasionally, it may be associated with diabetes or thyroid disease.

Its cause is unknown.


Presentation

Granuloma annulare is usually asymptomatic, but the rash may burn and be itchy. Patients usually notice a ring of small, firm bumps (papules) over the backs of the forearms, hands or feet, often centered around joints or knuckles. The bumps are caused by the clustering of T cells below the skin. Occasionally, multiple rings may be found. Rarely, granuloma annulare may appear as a firm nodule under the skin of the arms or legs.


Prognosis

Because granuloma annulare is usually asymptomatic, treatment may not be necessary except for cosmetic reasons. Most lesions of granuloma annulare disappear in pre-pubertal patients with no treatment within two years while older patients (50+) have rings for upwards of 20 years. The appearance of new rings years later is not uncommon.