Often increased
0No markers in this group.
Everyone Healthy Library
Hypophosphatemic Rickets
Condition / disease reference page from the Everyone Healthy database.
Connected health information
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Condition overview
Attributes
Commonalityis rare
Linked signs and symptoms
0No related signs or symptoms are listed yet.
Linked drugs / medications
1Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
0Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
No linked treatment or supportive options are listed yet.
Linked diagnostic tests and investigations
4These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
Biological and test markers
5This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often decreased
5- Alkaline Phosphatase (ALP)Reference range exampleAdult ( > 16y), Female: 30–125 units/L; Adult ( > 16y), Male: 40–110 units/LLinked diagnostic tests1Alkaline Phosphatase (ALP) Concentration
- Anion Gap (Excluding Potassium)Reference range exampleAll: 12–20 mEq/L; All: 8–16 mEq/LLinked diagnostic tests1Anion Gap
- Anion Gap (Including Potassium)Reference range exampleAll: 12–20 mEq/LLinked diagnostic tests1Anion Gap
- Calcium (Blood, Total)Reference range exampleAdult ( > 16y): 8.5–10.4 mg/dL; Birth - 2wks: 7.6–10.3 mg/dLLinked diagnostic tests1Calcium Concentration (Blood, Total)
- Phosphate (PO4, Phosphorus, P)Reference range exampleAdult ( > 16y): 2.5–4.5 mg/dL; Birth - 2wks: 4.3–9.2 mg/dLLinked diagnostic tests1Phosphate Concentration (PO4, Phosphorus)
Other associated markers
0No markers in this group.
Introduction / full article
Hypophosphatemic Rickets
Hypophosphatemic Rickets
Hypophosphatemic Rickets (Autosomal dominant hypophosphatemic rickets(ADHR)) is a rare hereditary disease in which excessive loss of phosphate in the urine leads to poorly formed bones (rickets), bone pain, and tooth abscesses. ADHR is caused by a mutation in the fibroblast growth factor 23 (FGF23). ADHR affects men and women equally; symptoms may become apparent at any point from childhood through early adulthood. Blood tests reveal low levels of phosphate (hypophosphatemia) and inappropriately normal levels of vitamin D. Treatment consists of increasing phosphate intake and high doses of vitamin D. Occasionally, hypophosphatemia may improve over time as urine losses of phosphate partially correct.