Everyone Healthy Library
Inflammatory Bowel Disease
Condition / disease reference page from the Everyone Healthy database.
Connected health information
Explore this condition in a clear order
Linked signs and symptoms
0No related signs or symptoms are listed yet.
Linked drugs / medications
3Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
4Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Linked diagnostic tests and investigations
21These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Alpha-1 Antitrypsin (AAT) Concentration
- Apolipoprotein B Concentration
- Carbon Monoxide (CO) Concentration
- Cerebrospinal Fluid Protein Concentration
- Coagulation Factor Assay (Blood Clotting Factors)
- erythrocyte Sedimentation Rate (ESR)
- Fecal Occult Blood Test
- Ferritin Concentration
- Fibrin Degradation Products (FDPs, Fibrin Split Products, FSPs, Fibrin Breakdown Products, Fbps)
- Fibrinogen Concentration test
- Fibrinopeptide A (FPA) Action Assay
- Folic Acid (Folate) Concentration
- haptoglobin (Hp) concentration
- Iron Concentration
- Lactose Tolerance Test
- Plasminogen Activity
- Platelet Count
- Protein C (PC ANtigen)
- Protein Electrophoresis (Blood, Serum Protein)
- Protein S Concentration
- Vitamin B12 (VB12) Concentration
Biological and test markers
24This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
15- Alpha-1 Antintrypsin (AAT)Reference range exampleAdult ( > 16y): 90–215 mg/dLLinked diagnostic tests1Alpha-1 Antitrypsin (AAT) Concentration
- Alpha-1-Globulin (Blood, Serum)Reference range exampleAll: 0.1–0.3 gm/dLLinked diagnostic tests1Protein Electrophoresis (Blood, Serum Protein)
- Alpha-2-Globulin (Blood, Serum)Reference range exampleAll: 0.6–1 gm/dLLinked diagnostic tests1Protein Electrophoresis (Blood, Serum Protein)
- Beta GlobulinReference range exampleAll: 0.7–1.2 gm/dLLinked diagnostic tests1Protein Electrophoresis (Blood, Serum Protein)
- Carbon Monoxide (CO)Reference range exampleAdult ( > 16y): 0–1.5 %Linked diagnostic tests1Carbon Monoxide (CO) Concentration
- Cerebrospinal Fluid Total ProteinReference range exampleAdult ( > 16y): 15–45 mg/dL; Child (< 10y): 15–70 mg/dLLinked diagnostic tests1Cerebrospinal Fluid Protein Concentration
- Erythrocyte Sedimentation RateReference range exampleAdult ( > 16y), Female: 0–20 mm/Hr; Adult ( > 16y), Male: 0–15 mm/HrLinked diagnostic tests1erythrocyte Sedimentation Rate (ESR)
- Factor VIII (Antihemophilic Globulin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 55–145 %Linked diagnostic tests1Coagulation Factor Assay (Blood Clotting Factors)
- Fecal BloodReference range exampleAll: 0–2 mLLinked diagnostic tests1Fecal Occult Blood Test
- Fibrin Split ProductsReference range exampleAll: 0–1 mg/dLLinked diagnostic tests1Fibrin Degradation Products (FDPs, Fibrin Split Products
- FibrinogenReference range exampleAdult ( > 16y): 150–400 mg/dLLinked diagnostic tests1Fibrinogen Concentration test
- Fibrinopeptide A (FPA)Reference range exampleAdult ( > 16y), Female: 0.7–3.1 mg/mL; Adult ( > 16y), Male: 0.35–2.5 mg/mLLinked diagnostic tests1Fibrinopeptide A (FPA) Action Assay
- haptoglobin (Hp)Reference range example45–200 mg/dLLinked diagnostic tests1haptoglobin (Hp) concentration
- PlasminogenReference range exampleAdult ( > 16y), Female: 65–153 %; Adult ( > 16y), Male: 70–120 %Linked diagnostic tests1Plasminogen Activity
- PlateletsReference range exampleChild (0 - 16y): 150–450 109/L; Adult ( > 16y): 135–380 109/LLinked diagnostic tests1Platelet Count
Often decreased
9- Albumin (Blood)Reference range exampleAdult ( > 16y): 37–52 gm/dL; Infant (0 - 1y): 4.4–5.4 gm/dLLinked diagnostic tests2Blood Albumin Concentration, Protein Electrophoresis (Blood
- Apolipoprotein B (Apo B)Reference range exampleAdult ( > 16y), Female: 47–115 mg/dL; Adult ( > 16y), Male: 52–120 mg/dLLinked diagnostic tests1Apolipoprotein B Concentration
- FerritinReference range exampleChild (0 - 16y): 7–140 µg/L; Adult ( > 16y), Female: 18–160 µg/LLinked diagnostic tests1Ferritin Concentration
- Folic Acid (Folate)Reference range exampleInfant (0 - 1y): 14–51 ng/mL; Child (0 - 16y): 5–21 ng/mLLinked diagnostic tests1Folic Acid (Folate) Concentration
- Increase in Glucose ConcentrationReference range exampleAdult ( > 16y): 20–60 mg/dLLinked diagnostic tests1Lactose Tolerance Test
- IronReference range exampleChild (0 - 16y): 50–120 µg/dL; Adult ( > 16y), Female: 50–150 µg/dLLinked diagnostic tests2Iron Concentration, Total Iron Binding Capacity (TIBC)
- Protein CReference range exampleAdult ( > 16y): 70–150 %Linked diagnostic tests1Protein C (PC ANtigen)
- Protein SReference range exampleAdult ( > 16y), Female: 50–120 %; Adult ( > 16y), Male: 55–120 %Linked diagnostic tests1Protein S Concentration
- Vitamin B12 (VB12)Reference range exampleAdult ( > 16y): 130–670 pmol/LLinked diagnostic tests1Vitamin B12 (VB12) Concentration
Other associated markers
0No markers in this group.
Introduction / full article
Inflammatory Bowel Disease
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Gotu Kola (Centella Asiatica, Hydrocotyle Asiatica)[1, 3, 4, 5, 6, 7, 8]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (There is insufficient evidence to support claims that Gotu Kola helps in the treatment of inflammatory bowel disease in any way. More research is needed.)
Grade of Evidence: low quality of evidence
Cats Claw (Uncaria Tomentosa) [1, 2]:
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: no recomendation (insufficient evidence to support claims that Cats Claw can help to treat inflammatory bowel disease)
Grade of Evidence: very low quality of evidence
* www.gradeworkinggroup.org
Summary References
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://www.nutrasanus.com/cats-claw.html
3. Winston, D., Maimes, S., Adaptogens: Herbs For Strength, Stamina, and Stress Relief, 2007, pp. 226-7
4. "A Double-Blind, Placebo-Controlled Study on the Effects of Gotu Kola (Centella asiatica) on Acoustic Startle Response in Healthy Subjects". Journal of Clinical Psychopharmacology. 20(6):680-684, December 2000. Bradwejn, Jacques MD, FRCPC *; Zhou, Yueping MD, PhD ++; Koszycki, Diana PhD *; Shlik, Jakov MD, PhD
5. B. M. Hausen (1993) "Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer." Contact Dermatitis 29 (4), 175–179 doi:10.1111/j.1600-0536.1993.tb03532.x
6. Cataldo, A., Gasbarro, V., et al., "Effectiveness of the Combination of Alpha Tocopherol, Rutin, Melilotus, and Centella asiatica in The Treatment of Patients With Chronic Venous Insufficiency", Minerva Cardioangiology, 2001, Apr; 49(2):159-63
7. http://en.wikipedia.org/wiki/Gotu_kola#Medicinal_effects
8. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/gotu-kola