Everyone Healthy Library
Liver Fibrosis
Condition / disease reference page from the Everyone Healthy database.
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Connected health information
Explore this condition in a clear order
Linked signs and symptoms
0No related signs or symptoms are listed yet.
Linked drugs / medications
0No linked drugs are listed yet.
Treatments, therapies and supportive options
13Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Medical therapy
1Alternative and complementary therapies
6- Celandine (Ukrain, Chelidonium Majus)Weakly Against(Very Low Evidence)
- Gotu Kola (Centella Asiatica, Hydrocotyle Asiatica)No Recommendation(Low Evidence)
- Indian Snakeroot (Rauvolfia, Rawolfia Serpentina)No Recommendation(Very Low Evidence)
- Licorice (Glycyrrhiza Glabra, Gan Cao)No Recommendation(Very Low Evidence)
- Neural TherapyNo Recommendation(Very Low Evidence)
- Turmeric
Alternative medicine
4Alternative therapies
1Linked diagnostic tests and investigations
48These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Acid Phosphatase Concentration
- Activated Coagulation Time (ACT)
- Activated Partial Thromboplastin Time (APTT)
- Alpha-1 Antitrypsin (AAT) Concentration
- Antithrombin 111 (AT-111) Activity Test
- Aspartate Aminotransferase (AST) Concentration
- Blood Uric Acid Concentration Test
- Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase)
- Coagulation Factor Assay (Blood Clotting Factors)
- Creatine Kinase Concentration
- D-Dimer Blood Test
- Fibrin Degradation Products (FDPs, Fibrin Split Products, FSPs, Fibrin Breakdown Products, Fbps)
- Fibrin Monomers Test
- Fibrinogen Concentration test
- Folic Acid (Folate) Concentration
- Gamma-Glutamyltransferase (GGT) Concentration
- Glucose Tolerance Test (GTT, OGTT, 120 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 160 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 30 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 60 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, Fasting Glucose)
- Glucose Tolerance Test for Gestational Diabetes (1 Hour After Glucose Load)
- Glucose Tolerance Test for Gestational Diabetes (Fasting Glucose Value)
- Glucose, Blood (Fasting Blood Glucose)
- Glucose, Blood (Post Prandiol Blood Glucose Test, 2 Hour Post Meal Blood Glucose)
- Glucose, Blood (Random Blood Glucose Test)
- haptoglobin (Hp) concentration
- Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Insulin Concentration (Insulin Assay, Serum Insulin)
- Lactate Dehydrogenase Concentration
- Lactic Acid Concentration
- lipase concentration
- Low Density Lipoprotein (LDL) Concentration
- Mean Corpuscular Volume (MCV)
- Osmolality, Blood (Serum Osmolality)
- Phenylketonuria Test
- Plasminogen Activity
- Potassium Concentration (K, Blood)
- Protein Electrophoresis (Blood, Serum Protein)
- Prothrombin Time (PT)
- Thrombin Time
- Thyroxine Binding Globulin Concentration (TBG, Thyroid Binding Globulin, Blood)
- Triiodothyronine (Free T3) Concentration
- Urine Amino Acid Concentration
- Urine bilirubin Concentration
- Urine Crystal Concentration
- Urine Sodium Quantitative (24hr)
- Vitamin B12 (VB12) Concentration
Biological markers/agents
76This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
55- 1 Methylhistidine (Urine)Reference range exampleChild (0 - 16y): 450–3,200 µmol/L; Adult ( > 16y): 700–8,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- 3 Methylhistidine (Urine)Reference range exampleChild (0 - 16y): 420–1,400 µmol/L; Adult ( > 16y): 650–3,300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Acid PhosphataseReference range exampleChild (0 - 16y), Male: 8.7–12.5 units/L; Adult ( > 16y), Male: 2.2–10.4 units/LLinked diagnostic testsAcid Phosphatase Concentration
- Alanine (Urine)Reference range exampleAdult ( > 16y): 1,500–7,000 µmol/L; Child (< 10y): 600–2,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alpha Amino N Buryric Acid (Urine)Reference range exampleAdult ( > 16y): 0–350 µmol/L; Child (< 10y): 80–300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alpha Aminoadipic Acid (Urine)Reference range exampleAdult ( > 16y): 0–1,700 µmol/L; Child (< 10y): 240–800 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alpha-1-Globulin (Blood, Serum)Reference range exampleAll: 0.1–0.3 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Arginine (Urine)Reference range exampleChild (0 - 16y): 120–260 µmol/L; Adult ( > 16y): 140–650 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Asparagine (Urine)Reference range exampleChild (0 - 16y): 160–420 µmol/L; Adult ( > 16y): 350–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Aspartate Aminotransferase (AST)Reference range exampleAdult ( > 16y), Female: 10–25 units/L; Adult ( > 16y), Male: 10–35 units/LLinked diagnostic testsAspartate Aminotransferase (AST) Concentration
- Aspartic Acid (Urine)Reference range exampleChild (0 - 16y): 110–270 µmol/L; Adult ( > 16y): 150–900 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Calcium Oxalate Crystals (Urine)Reference range exampleAll: 0–1 Not PresentLinked diagnostic testsUrine Crystal Concentration
- Carnosine (Urine)Reference range exampleChild (0 - 16y): 350–2,500 µmol/L; Adult ( > 16y): 170–1,300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Citrulline (Urine)Reference range exampleChild (0 - 16y): 0–140 µmol/L; Adult ( > 16y): 0–100 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Coagulation Bleeding TimeReference range exampleAdult ( > 16y): 65–110 secondsLinked diagnostic testsActivated Coagulation Time (ACT)
- Cystine (Urine)Reference range exampleChild (0 - 16y): 120–540 µmol/L; Adult ( > 16y): 300–1,200 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- D-DimerReference range exampleAdult ( > 16y): 0–240 µg/LLinked diagnostic testsD-Dimer Blood Test
- Fibrin MonomersReference range example0–10,000 µg/LLinked diagnostic testsFibrin Monomers Test
- Fibrin Split ProductsReference range exampleAll: 0–1 mg/dLLinked diagnostic testsFibrin Degradation Products (FDPs, Fibrin Split Products
- Gamma Globulin (Blood, Serum)Reference range exampleAll: 0.8–1.7 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Gamma-Glutamyltransferase (GGT)Reference range exampleAdult ( > 16y), Female: 6–30 units/L; Adult ( > 16y), Male: 6–38 units/LLinked diagnostic testsGamma-Glutamyltransferase (GGT) Concentration
- Glutamic Acid (Urine)Reference range exampleChild (0 - 16y): 135–240 µmol/L; Adult ( > 16y): 300–1,100 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Glutamine (Urine)Reference range exampleChild (0 - 16y): 1,600–4,000 µmol/L; Adult ( > 16y): 3,000–10,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Glycine (Urine)Reference range exampleChild (0 - 16y): 2,000–8,500 µmol/L; Adult ( > 16y): 8,000–25,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Histidine (Urine)Reference range exampleChild (0 - 16y): 500–7,300 µmol/L; Adult ( > 16y): 5,000–16,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Human Placental Lactogen (HPL, Pregnancy Weaks 25 to 30)Reference range exampleAdult ( > 16y), Female: 2,300–6,100 µg/LLinked diagnostic testsHuman Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (hPL, Pregnancy Weaks 31 to 35)Reference range exampleAdult ( > 16y), Female: 3,800–8,800 µg/LLinked diagnostic testsHuman Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (hPL, Pregnancy Weaks 36 to 40)Reference range exampleAdult ( > 16y), Female: 4,900–8,600 µg/LLinked diagnostic testsHuman Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (HPL, Pregnancy Weaks 5 to 25)Reference range exampleAdult ( > 16y), Female: 0–4,500 µg/LLinked diagnostic testsHuman Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- InsulinReference range exampleChild (0 - 16y): 3–15 µIU/mL; Adult ( > 16y): 6–28 µIU/mLLinked diagnostic testsInsulin Concentration (Insulin Assay, Serum Insulin)
- Isoleucine (Urine)Reference range exampleChild (0 - 16y): 40–150 µmol/L; Child (0 - 16y): 100–250 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Lactate Dehydrogenase (LDH)Reference range exampleInfant (0 - 1y): 120–250 units/L; Adult ( > 16y): 100–200 units/LLinked diagnostic testsLactate Dehydrogenase Concentration
- Lactic Acid (Venous Blood)Reference range exampleAll: 0.5–2.2 mEq/LLinked diagnostic testsLactic Acid Concentration
- LipaseReference range exampleAdult ( > 16y): 10–140 units/LLinked diagnostic testslipase concentration
- Low Density Lipoprotein (LDL)Reference range exampleAdult ( > 16y): 0–125 mg/dL; 6y - 16y: 0–100 mg/dLLinked diagnostic testsLow Density Lipoprotein (LDL) Concentration
- Lysine (Urine)Reference range exampleChild (0 - 16y): 200–1,500 µmol/L; Adult ( > 16y): 300–3,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Methionine (Urine)Reference range exampleChild (0 - 16y): 70–220 µmol/L; Adult ( > 16y): 55–320 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Ornithine (Urine)Reference range exampleChild (0 - 16y): 40–165 µmol/L; Adult ( > 16y): 50–800 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Osmolality, Blood (Serum Osmolality)Reference range exampleChild (0 - 16y): 274–290 mOsm/kg; Birth - 2wks: 265–285 mOsm/kgLinked diagnostic testsOsmolality, Blood (Serum Osmolality)
- PhenylalanineReference range exampleAdult ( > 16y): 0–16 mg/24hrs; Child (5 - 12y): 4–16.5 mg/24hrsLinked diagnostic testsPhenylketonuria Test
- Phenylalanine (Urine)Reference range exampleChild (0 - 16y): 200–600 µmol/L; Adult ( > 16y): 400–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Phosphoethanolamine (Urine)Reference range exampleChild (0 - 16y): 250–670 µmol/L; Adult ( > 16y): 200–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Phosphoserine (Urine)Reference range exampleChild (0 - 16y): 150–350 µmol/L; Child (0 - 16y): 1,000–2,200 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Plasma thromboplastin antecedentReference range exampleAdult ( > 16y): 20–35 secondsLinked diagnostic testsActivated Partial Thromboplastin Time (APTT)
- Proline (Urine)Reference range exampleChild (0 - 16y): 0–1 Not PresentLinked diagnostic testsUrine Amino Acid Concentration
- Red Blood Cell (RBC) VolumeReference range example76–100 fLLinked diagnostic testsMean Corpuscular Volume (MCV)
- Serine (Urine)Reference range exampleChild (0 - 16y): 1,000–2,200 µmol/L; Adult ( > 16y): 2,000–7,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Taurine (Urine)Reference range exampleChild (0 - 16y): 600–9,800 µmol/L; Adult ( > 16y): 2,700–13,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Threonine (Urine)Reference range exampleChild (0 - 16y): 250–1,000 µmol/L; Adult ( > 16y): 900–3,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Thrombin TimeReference range exampleAdult ( > 16y): 10–20 secondsLinked diagnostic testsThrombin Time
- Thyroxine Binding Globulin (TBG, Thyroid Binding Globulin, Blood)Reference range exampleInfant (0 - 1y), Female: 1.7–3.6 mg/dL; Infant (0 - 1y), Male: 1.6–3.5 mg/dLLinked diagnostic testsThyroxine Binding Globulin Concentration (TBG, Thyroid Binding Globulin
- Tyrosine (Urine)Reference range exampleChild (0 - 16y): 300–850 µmol/L; Adult ( > 16y): 400–1,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Urine bilirubinReference range exampleAll: 0–0.02 mg/dLLinked diagnostic testsUrine bilirubin Concentration
- Valine (Urine)Reference range exampleChild (0 - 16y): 200–400 µmol/L; Adult ( > 16y): 200–750 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Vitamin B12 (VB12)Reference range exampleAdult ( > 16y): 130–670 pmol/LLinked diagnostic testsVitamin B12 (VB12) Concentration
Often decreased
21- Albumin (Blood)Reference range exampleAdult ( > 16y): 37–52 gm/dL; Infant (0 - 1y): 4.4–5.4 gm/dLLinked diagnostic testsBlood Albumin Concentration, Protein Electrophoresis (Blood
- Alpha-1 Antintrypsin (AAT)Reference range exampleAdult ( > 16y): 90–215 mg/dLLinked diagnostic testsAlpha-1 Antitrypsin (AAT) Concentration
- Alpha-2-Globulin (Blood, Serum)Reference range exampleAll: 0.6–1 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Antithrombin 111 (AT-111)Reference range exampleAdult ( > 16y): 90–110 %Linked diagnostic testsAntithrombin 111 (AT-111) Activity Test
- CholinesteraseReference range exampleAll: 6–19 U/mLLinked diagnostic testsCholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase)
- Creatine Kinase (CK)Reference range exampleAdult ( > 16y), Female: 35–150 units/L; Adult ( > 16y), Male: 40–170 units/LLinked diagnostic testsCreatine Kinase Concentration
- Factor II (Prothrombin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 80–120 %; Adult ( > 16y): 80–120 %Linked diagnostic testsCoagulation Factor Assay (Blood CLotting Factors, Coagulation Factor Assay (Blood Clotting Factors)
- Factor IX (Christmas Factor, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 60–140 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Factor V (Labile Factor, Proaccelerin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 50–150 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Factor X (Stuart Prower Factor, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 45–155 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Factor XI (Plasma Thromboplastin Antecedent, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 65–135 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Factor XII (Hageman Factor, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 50–150 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- FibrinogenReference range exampleAdult ( > 16y): 150–400 mg/dLLinked diagnostic testsFibrinogen Concentration test
- Folic Acid (Folate)Reference range exampleInfant (0 - 1y): 14–51 ng/mL; Child (0 - 16y): 5–21 ng/mLLinked diagnostic testsFolic Acid (Folate) Concentration
- Glucose (Blood)Reference range exampleInfant (0 - 1y): 3–6.1 mmol/L; Adult ( > 16y): 0–6.1 mmol/LLinked diagnostic testsfasting Blood Glucose Test, Glucose Tolerance Test (GTT
- haptoglobin (Hp)Reference range example45–200 mg/dLLinked diagnostic testshaptoglobin (Hp) concentration
- PlasminogenReference range exampleAdult ( > 16y), Female: 65–153 %; Adult ( > 16y), Male: 70–120 %Linked diagnostic testsPlasminogen Activity
- Potassium (K, Blood)AbbreviationKReference range exampleInfant (0 - 1y): 4.1–5.3 mEq/L; Child (0 - 16y): 3.4–4.7 mEq/LLinked diagnostic testsPotassium Concentration (K, Blood)
- Triiodothyronine (Free T3)Reference range example2.7–4.9 pg/mLLinked diagnostic testsTriiodothyronine (Free T3) Concentration
- Uric Acid, BloodReference range exampleAdult ( > 16y), Female: 2.5–7 mg/dL; Adult ( > 16y), Male: 4–8 mg/dLLinked diagnostic testsBlood Uric Acid Concentration Test
- Urine SodiumReference range exampleChild (0 - 16y): 41–115 mmol/day; Adult ( > 16y): 40–220 mmol/dayLinked diagnostic testsUrine Sodium Quantitative (24hr)
Introduction / full article
Liver Fibrosis
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Turmeric [1, 16, 17, 18, 19, 20, 21]:
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (There is insufficient evidence to support claims that turmeric can help in the treatment of liver disease. More research is needed.)
Grade of Evidence: very low quality of evidence
Licorice (Glcyrhiz Gaba) [1, 12, 13, 14, 15]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present. Licorice has been shown to have potentially harmful side effects in people with high blood pressure, liver or kidney diseases)
Recommendation: No recommendation (There is insufficient evidence to support claims that licorice helps treat some symptoms of liver fibrosis. More research is needed)
Grade of Evidence: very low quality of evidence
Indian Snakeroot (Rauvolfia, Rawolfia Serpentina) [1, 10, 11]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (There is insufficient evidence to support claims that Indian Snakeroot helps to treat liver fibrosis in any way)
Grade of Evidence: very low quality of evidence
Gotu Kola (Centella Asiatica, Hydrocotyle Asiatica)[1, 4, 5, 6, 7, 8, 9]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (There is insufficient evidence to support claims that Gotu Kola helps in the treatment of liver fibrosis in any way. More research is needed.)
Grade of Evidence: low quality of evidence
Celandine (Ukrain, Chelidonium Majus) [1, 2, 3]:
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: weakly against (There is insufficient evidence that Celandine helps to cure or treat liver fibrosis. In addition, the plant is mildly poisonous to humans. It may cause hepatitis as well as symptoms of pain, nausea, thirst, and fever.)
Grade of Evidence: very low quality of evidence
Neural Therapy:
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: no recomendation (there is insufficient evidence to show that Neural Therapy helps in treating liver fibrosis in any way)
Grade of Evidence: very low quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://abchomeopathy.com/r.php/Chel
3.http://www.naturalstandard.com/index-abstract.asp?create-abstract=/monographs/herbssupplements/greatercelandine.asp
4. Winston, D., Maimes, S., Adaptogens: Herbs For Strength, Stamina, and Stress Relief, 2007, pp. 226-7
5. "A Double-Blind, Placebo-Controlled Study on the Effects of Gotu Kola (Centella asiatica) on Acoustic Startle Response in Healthy Subjects". Journal of Clinical Psychopharmacology. 20(6):680-684, December 2000. Bradwejn, Jacques MD, FRCPC *; Zhou, Yueping MD, PhD ++; Koszycki, Diana PhD *; Shlik, Jakov MD, PhD
6. B. M. Hausen (1993) "Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer." Contact Dermatitis 29 (4), 175–179 doi:10.1111/j.1600-0536.1993.tb03532.x
7. Cataldo, A., Gasbarro, V., et al., "Effectiveness of the Combination of Alpha Tocopherol, Rutin, Melilotus, and Centella asiatica in The Treatment of Patients With Chronic Venous Insufficiency", Minerva Cardioangiology, 2001, Apr; 49(2):159-63
8. http://en.wikipedia.org/wiki/Gotu_kola#Medicinal_effects
9. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/gotu-kola
10. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/indian-snakeroot
11. http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/seven/000092149.htm
12. Winston, David; Steven Maimes (2007). Adaptogens: Herbs for Strength, Stamina, and Stress Relief. Healing Arts Press.
13. http://www.ncbi.nlm.nih.gov/pubmed/15190039
14. http://nccam.nih.gov/health/licoriceroot/
15. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-licorice.html
16. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/turmeric
17. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-turmeric.html
18. http://nccam.nih.gov/health/turmeric/index.htm
19. http://news.bbc.co.uk/2/hi/health/1668932.stm
20. http://www.mirror.co.uk/news/top-stories/2009/10/28/curry-kills-cancer-cells-and-other-health-benefits-of-the-nations-favourite-dish-115875-21779950/
21. http://clinicaltrials.gov/ct2/results?term=turmeric
22. Garcia-Tsao G, Lim JK; Members of Veterans Affairs Hepatitis C Resource Center Program. Management and treatment of patients with cirrhosis and portal hypertension: recommendations from the Department of Veterans Affairs Hepatitis C Resource Center Program and the National Hepatitis C Program. Am J Gastroenterol. 2009;104:1802-1829.
23. Schuppan D, Afdhal NH. Liver cirrhosis. Lancet. 2008;371:838-851.
24. Mehta G, Rothstein KD. Health maintenance issues in cirrhosis. Med Clin North Am. 2009;93:901-915.
25. http://www.ncbi.nlm.nih.gov/pubmed/15690074
26. http://www.hcvadvocate.org/hepatitis/factsheets_pdf/Fibrosis.pdf
27. http://www.meddean.luc.edu/lumen/MedEd/orfpath/fibrosis.htm
28. http://www.medical.siemens.com/webapp/wcs/stores/servlet/PSGenericDisplay~q_catalogId~e_-111~a_langId~e_-111~a_pageId~e_103856~a_storeId~e_10001.htm
29. http://www.merck.com/mmpe/sec03/ch026/ch026b.html
30. http://www.puristat.com/livercleansing/fibrosis.aspx
31. http://encyclopedia.farlex.com/Liver+fibrosis
32. http://informahealthcare.com/doi/abs/10.1080/003655299750026272
33. http://www.nlm.nih.gov/medlineplus/ency/article/000255.htm