Everyone Healthy Library
Metachromatic Leukodystrophy
Also Known As: Arylsulfatase A Deficiency; Metachromatic Leukoencephalopathy
Condition / disease reference page from the Everyone Healthy database.
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Get urgent medical care now if there is any severe, sudden, rapidly worsening or worrying symptom, especially:
- chest pain, pressure or pain spreading to the arm, jaw or back
- trouble breathing, blue lips, severe wheeze or choking
- stroke-like symptoms such as face drooping, arm weakness or speech trouble
- collapse, fainting, seizure, confusion or extreme drowsiness
- severe bleeding, black stools, vomiting blood or major injury
- severe allergic reaction, swelling of the face/throat or widespread rash with breathing trouble
- severe abdominal pain, severe headache, stiff neck or sudden vision change
- signs of severe dehydration, sepsis, high fever with worsening illness, or symptoms in a baby/young child that concern you
Connected health information
Explore this condition in a clear order
Condition overview
Attributes
Linked signs and symptoms
13Each sign/symptom opens its own page and links back to related conditions.
- Behaviour: Bizarre Or Strange
- Behaviour: Disinhibition (Inability to Inhibit Inappropriate Behaviour)
- Behaviour: Impulsive Behaviour
- Eye: Vision Impairment
- Mind: Dementia
- Mind: Developmental Delay
- Mind: Mental Lability
- Muscle Tension
- Muscle Tightening
- Muscle Wasting
- Seizures
- Swallowing Difficulty (Dysphagia)
- Urinary Control Loss (Incontinence)
Linked drugs / medications
0No linked drugs are listed yet.
Treatments, therapies and supportive options
6Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Medical therapy
1Lifestyle changes
2Behavioural changes
2Linked diagnostic tests and investigations
4These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
Biological markers/agents
5This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
4- Asparagine (Urine)Reference range exampleChild (0 - 16y): 160–420 µmol/L; Adult ( > 16y): 350–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Aspartate Aminotransferase (AST)Reference range exampleAdult ( > 16y), Female: 10–25 units/L; Adult ( > 16y), Male: 10–35 units/LLinked diagnostic testsAspartate Aminotransferase (AST) Concentration
- Creatine Kinase3 (CK-MM) IsoenzymeReference range exampleAdult ( > 16y): 97–100 %Linked diagnostic testsCreatine Kinase Concentration
- Lysine (Urine)Reference range exampleChild (0 - 16y): 200–1,500 µmol/L; Adult ( > 16y): 300–3,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
Often decreased
1Introduction / full article
Metachromatic Leukodystrophy
The main information article for this record is not yet available in the database.