Everyone Healthy Library
Rickets
Condition / disease reference page from the Everyone Healthy database.
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Get urgent medical care now if there is any severe, sudden, rapidly worsening or worrying symptom, especially:
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Connected health information
Explore this condition in a clear order
Condition overview
Attributes
Ageis Infant
Commonalityis rare
Linked signs and symptoms
9Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
1Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
4Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Behavioural changes
1Vitamins and minerals
1Vitamins
1Linked diagnostic tests and investigations
5These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
Biological markers/agents
32This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
30- 1 Methylhistidine (Urine)Reference range exampleChild (0 - 16y): 450–3,200 µmol/L; Adult ( > 16y): 700–8,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- 3 Methylhistidine (Urine)Reference range exampleChild (0 - 16y): 420–1,400 µmol/L; Adult ( > 16y): 650–3,300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alanine (Urine)Reference range exampleAdult ( > 16y): 1,500–7,000 µmol/L; Child (< 10y): 600–2,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alkaline Phosphatase (ALP)Reference range exampleAdult ( > 16y), Female: 30–125 units/L; Adult ( > 16y), Male: 40–110 units/LLinked diagnostic testsAlkaline Phosphatase (ALP) Concentration
- Alpha Amino N Buryric Acid (Urine)Reference range exampleAdult ( > 16y): 0–350 µmol/L; Child (< 10y): 80–300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alpha Aminoadipic Acid (Urine)Reference range exampleAdult ( > 16y): 0–1,700 µmol/L; Child (< 10y): 240–800 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Arginine (Urine)Reference range exampleChild (0 - 16y): 120–260 µmol/L; Adult ( > 16y): 140–650 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Asparagine (Urine)Reference range exampleChild (0 - 16y): 160–420 µmol/L; Adult ( > 16y): 350–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Aspartic Acid (Urine)Reference range exampleChild (0 - 16y): 110–270 µmol/L; Adult ( > 16y): 150–900 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Carnosine (Urine)Reference range exampleChild (0 - 16y): 350–2,500 µmol/L; Adult ( > 16y): 170–1,300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Citrulline (Urine)Reference range exampleChild (0 - 16y): 0–140 µmol/L; Adult ( > 16y): 0–100 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Cystine (Urine)Reference range exampleChild (0 - 16y): 120–540 µmol/L; Adult ( > 16y): 300–1,200 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Glutamic Acid (Urine)Reference range exampleChild (0 - 16y): 135–240 µmol/L; Adult ( > 16y): 300–1,100 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Glutamine (Urine)Reference range exampleChild (0 - 16y): 1,600–4,000 µmol/L; Adult ( > 16y): 3,000–10,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Glycine (Urine)Reference range exampleChild (0 - 16y): 2,000–8,500 µmol/L; Adult ( > 16y): 8,000–25,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Histidine (Urine)Reference range exampleChild (0 - 16y): 500–7,300 µmol/L; Adult ( > 16y): 5,000–16,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Isoleucine (Urine)Reference range exampleChild (0 - 16y): 40–150 µmol/L; Child (0 - 16y): 100–250 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Lysine (Urine)Reference range exampleChild (0 - 16y): 200–1,500 µmol/L; Adult ( > 16y): 300–3,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Methionine (Urine)Reference range exampleChild (0 - 16y): 70–220 µmol/L; Adult ( > 16y): 55–320 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Ornithine (Urine)Reference range exampleChild (0 - 16y): 40–165 µmol/L; Adult ( > 16y): 50–800 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Parathyroid hormone (PTH, Parathormone)Reference range exampleAdult ( > 16y): 10–62 pg/mLLinked diagnostic testsParathyroid Hormone Concentration
- Phenylalanine (Urine)Reference range exampleChild (0 - 16y): 200–600 µmol/L; Adult ( > 16y): 400–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Phosphoethanolamine (Urine)Reference range exampleChild (0 - 16y): 250–670 µmol/L; Adult ( > 16y): 200–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Phosphoserine (Urine)Reference range exampleChild (0 - 16y): 150–350 µmol/L; Child (0 - 16y): 1,000–2,200 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Proline (Urine)Reference range exampleChild (0 - 16y): 0–1 Not PresentLinked diagnostic testsUrine Amino Acid Concentration
- Serine (Urine)Reference range exampleChild (0 - 16y): 1,000–2,200 µmol/L; Adult ( > 16y): 2,000–7,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Taurine (Urine)Reference range exampleChild (0 - 16y): 600–9,800 µmol/L; Adult ( > 16y): 2,700–13,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Threonine (Urine)Reference range exampleChild (0 - 16y): 250–1,000 µmol/L; Adult ( > 16y): 900–3,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Tyrosine (Urine)Reference range exampleChild (0 - 16y): 300–850 µmol/L; Adult ( > 16y): 400–1,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Valine (Urine)Reference range exampleChild (0 - 16y): 200–400 µmol/L; Adult ( > 16y): 200–750 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
Often decreased
2- Calcium (Blood, Total)Reference range exampleAdult ( > 16y): 8.5–10.4 mg/dL; Birth - 2wks: 7.6–10.3 mg/dLLinked diagnostic testsCalcium Concentration (Blood, Total)
- Phosphate (PO4, Phosphorus, P)Reference range exampleAdult ( > 16y): 2.5–4.5 mg/dL; Birth - 2wks: 4.3–9.2 mg/dLLinked diagnostic testsPhosphate Concentration (PO4, Phosphorus)
Introduction / full article
Rickets
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Vitamin D [1, 2, 3, 4, 5, 6, 7, 8, 9, 10]:
Please note, this management does NOT treat the condition itself. It may mildly help in preventing some of the symptoms, and even then has insufficient evidence to back up this claim at present. Please note, this acts as a PREVENTATIVE treatment, and not necessarily symptomatic relief.
Recommendation: strongly in favor (Studies have shown that a Vitamin D can help to prevent and treat rickets)
Grade of Evidence: high quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/vitamin-d
2. http://onlinelibrary.wiley.com/o/cochrane/clsysrev/articles/CD006164/frame.html
3. http://www.ncbi.nlm.nih.gov/pubmed/10824056
4. http://onlinelibrary.wiley.com/doi/10.1002/jcb.10338/abstract
5. http://pain-topics.org/pdf/vitamind-report.pdf
6. http://informahealthcare.com/doi/abs/10.1185/030079908X253519
7. http://www.theglobeandmail.com/life/article756975.ece
8. http://www.ncbi.nlm.nih.gov/pubmed/17556697
9. http://www.ncbi.nlm.nih.gov/pubmed/18065602
10. http://www.nlm.nih.gov/medlineplus/vitamind.html