Everyone Healthy Library
Subclinical Hyperthyroidism
Condition / disease reference page from the Everyone Healthy database.
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Connected health information
Explore this condition in a clear order
Linked signs and symptoms
6Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
0No linked drugs are listed yet.
Treatments, therapies and supportive options
3Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Vitamins and minerals
1Minerals
1Linked diagnostic tests and investigations
17These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Calcium Concentration (Blood, Total)
- Coagulation Factor Assay (Blood Clotting Factors)
- Creatinine Concentration (Blood, Serum Creatinine)
- Fetal Hemoglobin (Hemoglobin F, HbF) Concentration
- Glucose Tolerance Test (GTT, OGTT, 120 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 160 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 30 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 60 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, Fasting Glucose)
- Glucose Tolerance Test for Gestational Diabetes (1 Hour After Glucose Load)
- Glucose Tolerance Test for Gestational Diabetes (Fasting Glucose Value)
- Glucose, Blood (Post Prandiol Blood Glucose Test, 2 Hour Post Meal Blood Glucose)
- Protein Electrophoresis (Blood, Serum Protein)
- Thyroxine (Total T4) Concentration
- Thyroxine Binding Globulin Concentration (TBG, Thyroid Binding Globulin, Blood)
- Urine Estradiol (E2) Concetration
- Urine Hydroxyproline Concentration
Biological markers/agents
12This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
8- Calcium (Blood, Total)Reference range exampleAdult ( > 16y): 8.5–10.4 mg/dL; Birth - 2wks: 7.6–10.3 mg/dLLinked diagnostic testsCalcium Concentration (Blood, Total)
- Creatinine (Blood)Reference range exampleInfant (0 - 1y): 0.1–0.4 mg/dL; Adult ( > 16y), Female: 0.6–1.2 mg/dLLinked diagnostic testsCreatinine Concentration (Blood, Serum Creatinine)
- Factor VIII (Antihemophilic Globulin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 55–145 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Fetal Hemoglobin (Hemoglobin F, HbF)Reference range exampleAdult ( > 16y): 0–2.1 %; Birth - 2wks: 56–90 %Linked diagnostic testsFetal Hemoglobin (Hemoglobin F, HbF) Concentration
- Glucose (Blood)Reference range exampleInfant (0 - 1y): 3–6.1 mmol/L; Adult ( > 16y): 0–6.1 mmol/LLinked diagnostic testsfasting Blood Glucose Test, Glucose Tolerance Test (GTT
- Hydroxyproline (Urine Excretion Rate)Reference range exampleAdult ( > 16y): 14–45 mg/24hrs; Adult ( > 16y), Female: 0.4–2.9 mg/2hrsLinked diagnostic testsUrine Amino Acid Concentration, Urine Hydroxyproline Concentration
- Thyroxine (Total T4)Reference range exampleAdult ( > 16y), Female: 6–12 µg/dL; Adult ( > 16y), Male: 5–12 µg/dLLinked diagnostic testsThyroxine (Total T4) Concentration
- Urine Estradiol (E2)Reference range exampleAdult ( > 16y), Female: 0–15 µg/24hrs; Adult ( > 16y), Male: 0–6.5 µg/24hrsLinked diagnostic testsUrine Estradiol (E2) Concetration
Often decreased
4- Albumin (Blood)Reference range exampleAdult ( > 16y): 37–52 gm/dL; Infant (0 - 1y): 4.4–5.4 gm/dLLinked diagnostic testsBlood Albumin Concentration, Protein Electrophoresis (Blood
- Alpha-1-Globulin (Blood, Serum)Reference range exampleAll: 0.1–0.3 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Alpha-2-Globulin (Blood, Serum)Reference range exampleAll: 0.6–1 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Thyroxine Binding Globulin (TBG, Thyroid Binding Globulin, Blood)Reference range exampleInfant (0 - 1y), Female: 1.7–3.6 mg/dL; Infant (0 - 1y), Male: 1.6–3.5 mg/dLLinked diagnostic testsThyroxine Binding Globulin Concentration (TBG, Thyroid Binding Globulin
Introduction / full article
Subclinical Hyperthyroidism
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Selenium Supplement [1, 2, 3, 4, 5, 6, 7, 8, 8, 9, 10]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present. IMPORTANT: Selenium is toxic in high doses. Massive overdoses can cause kidney failure, breathing difficulty and death. Selenium should only be taken at healthy levels which the body is able to tolerate.
Recommendation: No recommendation (Available evidene does not support claims that selenium helps to prevent or treat any thyroid conditions)
Grade of Evidence: very low quality of evidence
Black Walnut (Juglans Nigra):
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (Available evidence does not support claims that Black Walnut helps to treat hyperthyroidism)
Grade of Evidence: low quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/selenium?sitearea=ETO
3. http://www.cancer.gov/Templates/doc.aspx?viewid=ED8AD8E8-6AE5-458D-8091-393F4CB73F0D
4. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-selenium.html
5. http://www.ncbi.nlm.nih.gov/pubmed/9290116
6. http://www.ncbi.nlm.nih.gov/pubmed/9829869
7. http://www.ncbi.nlm.nih.gov/pubmed/10335455
8. http://www.ncbi.nlm.nih.gov/pubmed/2136228
9. http://www.springerlink.com/content/v0r644v4ju5153k2/
10. http://jnci.oxfordjournals.org/cgi/content/full/101/5/283