Everyone Healthy Library
Syphilis
Condition / disease reference page from the Everyone Healthy database.
Connected health information
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Condition overview
Attributes
Linked signs and symptoms
4Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
6Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
2Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Alternative medicine
1Linked diagnostic tests and investigations
6These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
Biological and test markers
5This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
5- Albumin (Cerebrospinal Fluid, CSF)Reference range exampleAll: 10–35 mg/dL; All: 56–76 %Linked diagnostic tests2Cerebrospinal Fluid Albumin Concentration, Cerebrospinal Fluid Protein Electrophoresis
- Cerebrospinal Fluid Total ProteinReference range exampleAdult ( > 16y): 15–45 mg/dL; Child (< 10y): 15–70 mg/dLLinked diagnostic tests1Cerebrospinal Fluid Protein Concentration
- Erythrocyte Sedimentation RateReference range exampleAdult ( > 16y), Female: 0–20 mm/Hr; Adult ( > 16y), Male: 0–15 mm/HrLinked diagnostic tests1erythrocyte Sedimentation Rate (ESR)
- MonocytesReference range exampleAdult ( > 16y): 3–7 %; 0.1–0.5 million/mLLinked diagnostic tests2Differential White Blood Cell Count Tests, Monocyte Absolute Count
- Treponema Pallidum Specific Antibodies (FTA ABS, Syphilis Serology)Reference range exampleAll: 0–1 NegativeLinked diagnostic tests1Treponema Pallidum Serology Test (FTA ABS, Syphilis Serology)
Often decreased
0No markers in this group.
Other associated markers
0No markers in this group.
Introduction / full article
Syphilis
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Gotu Kola (Centella Asiatica, Hydrocotyle Asiatica)[1, 2, 3, 4, 5, 6, 7]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (There is insufficient evidence to support claims that Gotu Kola helps in the treatment of syphilis in any way. More research is needed.)
Grade of Evidence: low quality of evidence
* www.gradeworkinggroup.org
Summary References
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. Winston, D., Maimes, S., Adaptogens: Herbs For Strength, Stamina, and Stress Relief, 2007, pp. 226-7
3. "A Double-Blind, Placebo-Controlled Study on the Effects of Gotu Kola (Centella asiatica) on Acoustic Startle Response in Healthy Subjects". Journal of Clinical Psychopharmacology. 20(6):680-684, December 2000. Bradwejn, Jacques MD, FRCPC *; Zhou, Yueping MD, PhD ++; Koszycki, Diana PhD *; Shlik, Jakov MD, PhD
4. B. M. Hausen (1993) "Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer." Contact Dermatitis 29 (4), 175–179 doi:10.1111/j.1600-0536.1993.tb03532.x
5. Cataldo, A., Gasbarro, V., et al., "Effectiveness of the Combination of Alpha Tocopherol, Rutin, Melilotus, and Centella asiatica in The Treatment of Patients With Chronic Venous Insufficiency", Minerva Cardioangiology, 2001, Apr; 49(2):159-63
6. http://en.wikipedia.org/wiki/Gotu_kola#Medicinal_effects
7. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/gotu-kola