Everyone Healthy Library
Urinary Tract Infection (Cystitis)
Condition / disease reference page from the Everyone Healthy database.
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Connected health information
Explore this condition in a clear order
Condition overview
Attributes
Linked signs and symptoms
15Each sign/symptom opens its own page and links back to related conditions.
- Blood in Urine (Hematuria)
- Chills
- Fever (Raised Body Temperature)
- Mind: Confusion
- Pain Abdominal
- Pain During Urination (Dysuria)
- Pain: Lower Abdomen
- Urinary Control Loss (Incontinence)
- Urinary Frequency Increased
- Urinary Urgency
- Urination Increase At Night (Nocturia)
- Urination: Continuous Dribbling After Passing Urine
- Urine with Pus Present (Pyuria)
- Urine: Offensive Smell
- White Blood Cells Raised
Linked drugs / medications
12Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
11Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Alternative and complementary therapies
5Alternative medicine
2Alternative therapies
1Vitamins and minerals
1Vitamins
1Linked diagnostic tests and investigations
35These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Alpha-1 Antitrypsin (AAT) Concentration
- Cerebrospinal Fluid Albumin Concentration
- Cerebrospinal Fluid Glucose Concentration
- Cerebrospinal Fluid Protein Concentration
- Cerebrospinal Fluid Protein Electrophoresis
- Cerebrospinal Fluid White Cell Differential
- Chloride Concentration (Blood)
- Cholesterol Concentration
- Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase)
- D-Dimer Blood Test
- Eosinophils Count
- Ferritin Concentration
- Fibrin Degradation Products (FDPs, Fibrin Split Products, FSPs, Fibrin Breakdown Products, Fbps)
- Fibrin Monomers Test
- Fibrinogen Concentration test
- Fibrinopeptide A (FPA) Action Assay
- Glucagon Concentration Test
- Glucose 6 Phosphate Dehydrogenase (G6PD) Concentration
- haptoglobin (Hp) concentration
- Neutrophil Absolute Count
- Plasminogen Activity
- Potassium Concentration (K, Blood)
- Prostate-Specific Antigen (PSA) Blood Test
- Protein Electrophoresis (Blood, Serum Protein)
- Urine Appearance
- Urine Crystal Concentration
- Urine glucose concentration
- Urine Granular Cast Concentration
- Urine Haemologlobin (Hb) Concentration
- Urine Leukocyte Esterase Screening
- Urine Nitrate Concentration
- Urine pH Test
- Urine Red Blood Cells Concentration
- Urine White Blood Cells Test
- White Blood Cell (WBC) Count
Biological markers/agents
40This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
35- Albumin (Cerebrospinal Fluid, CSF)Reference range exampleAll: 10–35 mg/dL; All: 56–76 %Linked diagnostic testsCerebrospinal Fluid Albumin Concentration, Cerebrospinal Fluid Protein Electrophoresis
- Alpha-1 Antintrypsin (AAT)Reference range exampleAdult ( > 16y): 90–215 mg/dLLinked diagnostic testsAlpha-1 Antitrypsin (AAT) Concentration
- Alpha-1-Globulin (Blood, Serum)Reference range exampleAll: 0.1–0.3 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Alpha-2-Globulin (Blood, Serum)Reference range exampleAll: 0.6–1 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- AmmoniaReference range exampleAdult ( > 16y): 6–48 µmol/LLinked diagnostic testsAmmonia Concentration Test
- Beta GlobulinReference range exampleAll: 0.7–1.2 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Cerebrospinal Fluid LeukocytesReference range exampleAdult ( > 16y): 0–5 /µL; 1y - 6y: 0–20 /µLLinked diagnostic testsCerebrospinal Fluid White Cell Differential
- Cerebrospinal Fluid Total ProteinReference range exampleAdult ( > 16y): 15–45 mg/dL; Child (< 10y): 15–70 mg/dLLinked diagnostic testsCerebrospinal Fluid Protein Concentration
- Cholesterol (Total)Reference range exampleInfant (0 - 1y): 75–180 mg/dL; Adult ( > 16y): 0–190 mg/dLLinked diagnostic testsCholesterol Concentration
- D-DimerReference range exampleAdult ( > 16y): 0–240 µg/LLinked diagnostic testsD-Dimer Blood Test
- EosinophilsReference range exampleAdult ( > 16y): 0–3 %; 0–3 %Linked diagnostic testsDifferential White Blood Cell Count Tests, Eosinophil Differential Of Total WBC
- FerritinReference range exampleChild (0 - 16y): 7–140 µg/L; Adult ( > 16y), Female: 18–160 µg/LLinked diagnostic testsFerritin Concentration
- Fibrin MonomersReference range example0–10,000 µg/LLinked diagnostic testsFibrin Monomers Test
- Fibrin Split ProductsReference range exampleAll: 0–1 mg/dLLinked diagnostic testsFibrin Degradation Products (FDPs, Fibrin Split Products
- FibrinogenReference range exampleAdult ( > 16y): 150–400 mg/dLLinked diagnostic testsFibrinogen Concentration test
- Fibrinopeptide A (FPA)Reference range exampleAdult ( > 16y), Female: 0.7–3.1 mg/mL; Adult ( > 16y), Male: 0.35–2.5 mg/mLLinked diagnostic testsFibrinopeptide A (FPA) Action Assay
- Forced Expiratory Volume At Three Seconds (FEV3)Reference range exampleAll: 95–100 %Linked diagnostic testsSpirometry
- Gamma Globulin (Blood, Serum)Reference range exampleAll: 0.8–1.7 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- GlucagonReference range exampleChild (0 - 16y): 0–147 pg/mL; Adult ( > 16y): 20–110 pg/mLLinked diagnostic testsGlucagon Concentration Test
- haptoglobin (Hp)Reference range example45–200 mg/dLLinked diagnostic testshaptoglobin (Hp) concentration
- PlasminogenReference range exampleAdult ( > 16y), Female: 65–153 %; Adult ( > 16y), Male: 70–120 %Linked diagnostic testsPlasminogen Activity
- Potassium (K, Blood)AbbreviationKReference range exampleInfant (0 - 1y): 4.1–5.3 mEq/L; Child (0 - 16y): 3.4–4.7 mEq/LLinked diagnostic testsPotassium Concentration (K, Blood)
- PrealbuminReference range exampleAll: 2–7 %Linked diagnostic testsCerebrospinal Fluid Protein Electrophoresis
- Prostate Specific Antigen (PSA)Reference range exampleAdult ( > 16y), Male: 0–3.8 ng/mLLinked diagnostic testsProstate-Specific Antigen (PSA) Blood Test
- Segmented NeutrophilsReference range exampleAdult ( > 16y): 50–62 %; Adult ( > 16y): 2,500–8,000 mm3Linked diagnostic testsDifferential White Blood Cell Count Tests, Neutrophil Absolute Count
- Triple Phosphate Crystals (Urine)Reference range exampleAll: 0–1 Not PresentLinked diagnostic testsUrine Crystal Concentration
- Unrine Granular CastsReference range exampleAdult ( > 16y): 0–0 Not PresentLinked diagnostic testsUrine Granular Cast Concentration
- Urine Crystals (Total)Reference range example0–2 /hpfLinked diagnostic testsUrine Crystal Concentration
- Urine glucoseReference range example0–2.5; Adult ( > 16y): 0–2.5 mmol/dayLinked diagnostic testsUrine glucose concentration
- Urine Haemoglobin (Hb)Reference range exampleAdult ( > 16y): 0–0.02 mg/dLLinked diagnostic testsUrine Haemologlobin (Hb) Concentration
- Urine Leukocyte EsteraseReference range exampleAll: 0–1 Not PresentLinked diagnostic testsUrine Leukocyte Esterase Screening
- Urine NitrateReference range exampleAll: 0–0 Not PresentLinked diagnostic testsUrine Nitrate Concentration
- Urine Red Blood CellsReference range exampleAdult ( > 16y): 0–2 /hpfLinked diagnostic testsUrine Red Blood Cells Concentration
- Urine White Blood CellsReference range exampleAll: 0–5 /hpfLinked diagnostic testsUrine White Blood Cells Test
- White Blood Cell (WBC)Reference range exampleAdult ( > 16y): 4.5–10.5 million/mL; Adult ( > 16y): 3.2–10 million/mLLinked diagnostic testsWhite Blood Cell (WBC) Count
Often decreased
5- Chloride (Blood, Cl)Reference range exampleAdult ( > 16y): 97–106 mEq/L; Birth - 2wks: 94–106 mEq/LLinked diagnostic testsChloride Concentration (Blood)
- CholinesteraseReference range exampleAll: 6–19 U/mLLinked diagnostic testsCholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase)
- Glucose (Cerebrospinal Fluid)Reference range exampleChild (0 - 16y): 65–85 mg/dL; Adult ( > 16y): 50–72 mg/dLLinked diagnostic testsCerebrospinal Fluid Glucose Concentration
- Glucose 6 Phosphate Dehydrogenase (G6PD)Reference range exampleAdult ( > 16y): 10.1–18.5 U/gHb; Birth - 2wks: 12–23 U/gHbLinked diagnostic testsGlucose 6 Phosphate Dehydrogenase (G6PD) Concentration
- Subjective Urine CloudinessLinked diagnostic testsUrine Appearance
Introduction / full article
Urinary Tract Infection (Cystitis)
Urinary Tract Infection
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Vitamin A [1, 15, 16, 17, 18, 19, 20, 21]:
Please note, this management does NOT treat the condition itself. It may mildly help in preventing some of the symptoms, and even then has insufficient evidence to back up this claim at present. Please note, this acts as a PREVENTATIVE treatment, and not necessarily symptomatic relief.
Recommendation: Strongly in favor (Vitamin A may help to prevent urinary tract infections due to its role in the body's immune function)
Grade of Evidence: high quality of evidence
Gotu Kola (Centella Asiatica, Hydrocotyle Asiatica) [1, 9, 10, 11, 12, 13, 14]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (There is insufficient evidence to support claims that Gotu Kola helps in the treatment of Urinary Tract Infections in any way. More research is needed.)
Grade of Evidence: low quality of evidence
Goldenseal (Hydrastis Canadensis) [1, 2, 3, 4, 5, 6, 7, 8]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: Weakly against (There is insufficient evidence to support claims that Goldenseal helps to treat Urinary Tract Infections. More studies are needed. Goldenseal may produce toxic effects, including depression, constipation, rapid heartbeat, stomach pain, mouth ulcers and vomiting.)
Grade of Evidence: low quality of evidence
Aromatherapy:
Recommendation: no recommendation (early trials done show no support of claims that aromatherapy may help with cystitis)
Grade of Evidence: very low quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/goldenseal
3. http://nccam.nih.gov/health/goldenseal/
4. Tierra Michael (1998): The Way of Herbs. New York, Pocket Books
5. Grieve M. (1971): A Modern Herbal. New York, Dover Publications, Inc
6. Mills S. and Bone K. (2000): Principles and Practice of Phytotherapy. Philadelphia, Churchill Livingstone
7. Tice Raymond (1997): Goldenseal and Two of its constituent alkaloids: berberine and hydrastine Research Triangle Park, National Institute of Environmental Health Sciences, in Seiger E: Review of Toxilogical Literature
8. http://www.henriettesherbal.com/eclectic/ellingwood/hydrastis.html
9. Winston, D., Maimes, S., Adaptogens: Herbs For Strength, Stamina, and Stress Relief, 2007, pp. 226-7
10. "A Double-Blind, Placebo-Controlled Study on the Effects of Gotu Kola (Centella asiatica) on Acoustic Startle Response in Healthy Subjects". Journal of Clinical Psychopharmacology. 20(6):680-684, December 2000. Bradwejn, Jacques MD, FRCPC *; Zhou, Yueping MD, PhD ++; Koszycki, Diana PhD *; Shlik, Jakov MD, PhD
11. B. M. Hausen (1993) "Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer." Contact Dermatitis 29 (4), 175–179 doi:10.1111/j.1600-0536.1993.tb03532.x
12. Cataldo, A., Gasbarro, V., et al., "Effectiveness of the Combination of Alpha Tocopherol, Rutin, Melilotus, and Centella asiatica in The Treatment of Patients With Chronic Venous Insufficiency", Minerva Cardioangiology, 2001, Apr; 49(2):159-63
13. http://en.wikipedia.org/wiki/Gotu_kola#Medicinal_effects
14. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/gotu-kola
15. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-vitamina.html
16. http://www.nlm.nih.gov/medlineplus/vitamina.html
17. http://ods.od.nih.gov/factsheets/vitamina.asp
18. http://www.who.int/nutrition/topics/vad/en/
19. Latham, Michael E. (1997). Human Nutrition in the Developing World (Fao Food and Nutrition Paper). Food & Agriculture Organization of the United. ISBN 92-5-103818-X.
20. Sommer, Alfred (1995). Vitamin a Deficiency and Its Consequences: A Field Guide to Detection and Control. Geneva: World Health Organization. ISBN 92-4-154478-3.
21. http://www.unicef.org/worldfitforchildren/files/A-RES-S27-2E.pdf