Everyone Healthy Library
Aplastic Anemia
Condition / disease reference page from the Everyone Healthy database.
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Connected health information
Explore this condition in a clear order
Linked signs and symptoms
14Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
0No linked drugs are listed yet.
Treatments, therapies and supportive options
6Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Linked diagnostic tests and investigations
29These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- 2,3 Diphosphoglycerate (2,3-DPG) Concentration
- Bleeding Time (Ivy Method)
- Blood Tests
- Blood Uric Acid Concentration Test
- Bone Marrow Test
- Chloride Concentration (Blood)
- Cholesterol Concentration
- Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase)
- complete Blood Count (CBC)
- Eosinophils Count
- erythrocyte Sedimentation Rate (ESR)
- Erythropoietin (Ep) Concentration
- Erythropoietin (Ep) Concentration
- Fecal Urobilinogen Concentration
- Ferritin Concentration
- Fetal Hemoglobin (Hemoglobin F, HbF) Concentration
- Fibrinogen Concentration test
- Heamatocrit (Hct)
- Hemoglobin (Hb) Concentration
- Iron Concentration
- Lymphocytes Count
- Monocyte Absolute Count
- Oxygen Saturation Test (Arterial Blood, SaO2)
- Partial Pressure of Arterial Carbon Dioxide (PCO2, PaCO2)
- Partial Pressure of Oxygen (PO2)
- Red Blood Cell (RBC) Count
- Reticulocyte Absolute Count
- Vitamin B12 (VB12) Concentration
- White Blood Cell (WBC) Count
Biological markers/agents
25This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
11- 2,3 Diphosphoglycerate (2,3-DPG)Reference range exampleAdult ( > 16y): 10.5–14 µmol/gLinked diagnostic tests2, 3 Diphosphoglycerate (2
- Chloride (Blood, Cl)Reference range exampleAdult ( > 16y): 97–106 mEq/L; Birth - 2wks: 94–106 mEq/LLinked diagnostic testsChloride Concentration (Blood)
- Cholesterol (Total)Reference range exampleInfant (0 - 1y): 75–180 mg/dL; Adult ( > 16y): 0–190 mg/dLLinked diagnostic testsCholesterol Concentration
- Erythrocyte Sedimentation RateReference range exampleAdult ( > 16y), Female: 0–20 mm/Hr; Adult ( > 16y), Male: 0–15 mm/HrLinked diagnostic testserythrocyte Sedimentation Rate (ESR)
- Erythropoietin (Ep)Reference range exampleAdult ( > 16y): 6–36 units/LLinked diagnostic testsErythropoietin (Ep) Concentration
- FerritinReference range exampleChild (0 - 16y): 7–140 µg/L; Adult ( > 16y), Female: 18–160 µg/LLinked diagnostic testsFerritin Concentration
- Fetal Hemoglobin (Hemoglobin F, HbF)Reference range exampleAdult ( > 16y): 0–2.1 %; Birth - 2wks: 56–90 %Linked diagnostic testsFetal Hemoglobin (Hemoglobin F, HbF) Concentration
- IronReference range exampleChild (0 - 16y): 50–120 µg/dL; Adult ( > 16y), Female: 50–150 µg/dLLinked diagnostic testsIron Concentration, Total Iron Binding Capacity (TIBC)
- Template Bleeding TimeReference range exampleAdult ( > 16y): 2.5–9 MinutesLinked diagnostic testsBleeding Time (Ivy Method)
- Uric Acid, BloodReference range exampleAdult ( > 16y), Female: 2.5–7 mg/dL; Adult ( > 16y), Male: 4–8 mg/dLLinked diagnostic testsBlood Uric Acid Concentration Test
- White Blood Cell (WBC)Reference range exampleAdult ( > 16y): 4.5–10.5 million/mL; Adult ( > 16y): 3.2–10 million/mLLinked diagnostic testsWhite Blood Cell (WBC) Count
Often decreased
14- CholinesteraseReference range exampleAll: 6–19 U/mLLinked diagnostic testsCholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase)
- EosinophilsReference range exampleAdult ( > 16y): 0–3 %; 0–3 %Linked diagnostic testsDifferential White Blood Cell Count Tests, Eosinophil Differential Of Total WBC
- FibrinogenReference range exampleAdult ( > 16y): 150–400 mg/dLLinked diagnostic testsFibrinogen Concentration test
- Hemoglobin (Hb)Reference range exampleFemale: 78–100 gm/dL; Male: 76–100 gm/dLLinked diagnostic testsHemoglobin (Hb) Concentration, Mean Corpuscular Hemoglobin (MCH) Weight Test
- LymphocytesReference range exampleAdult ( > 16y): 25–40 %; 700–3,500 cells/mm3Linked diagnostic testsDifferential White Blood Cell Count Tests, Lymphocytes Count
- MonocytesReference range exampleAdult ( > 16y): 3–7 %; 0.1–0.5 million/mLLinked diagnostic testsDifferential White Blood Cell Count Tests, Monocyte Absolute Count
- Oxygen Saturation (Arterial Blood, SaO2)Reference range exampleChild (0 - 16y): 95–100 %; Newborn (0 - 1month): 40–90 %Linked diagnostic testsOxygen Saturation Test (Arterial Blood, SaO2)
- Partial Pressure of Arterial Carbon Dioxide (PaCO2)Reference range exampleAll: 35–45 mm HgLinked diagnostic testsPartial Pressure of Arterial Carbon Dioxide (PCO2, PaCO2)
- Partial Pressure of Arterial Oxygen (PaO2)Reference range exampleChild (0 - 16y): 80–100 mm Hg; Newborn (0 - 1month): 60–70 mm HgLinked diagnostic testsPartial Pressure of Oxygen (PO2)
- RBC MassReference range exampleFemale: 36–48 %; Male: 42–52 %Linked diagnostic testsHeamatocrit (Hct)
- Red Blood Cells (RBC)Reference range exampleAdult ( > 16y), Female: 3.6–5 106/mm3; Adult ( > 16y), Male: 4.2–5.4 106/mm3Linked diagnostic testsRed Blood Cell (RBC) Count
- ReticulocytesReference range exampleAdult ( > 16y): 24–83 109/L; 0.5–1.5 %Linked diagnostic testsReticulocyte Absolute Count, Reticulocyte Count Percent Total RBC
- Urobilinogen (Stools)Reference range exampleAll: 50–300 mg/24hrsLinked diagnostic testsFecal Urobilinogen Concentration
- Vitamin B12 (VB12)Reference range exampleAdult ( > 16y): 130–670 pmol/LLinked diagnostic testsVitamin B12 (VB12) Concentration
Introduction / full article
Aplastic Anemia
Aplastic Anemia
Aplastic anaemia is a disorder in which stem cells within the bone marrow fail to develop into mature blood cells and platelets. The result is that the bone marrow’s total output of blood cells is inadequate to meet the body’s requirements.
Aplastic anaemia differs from normal anaemia in that normal anaemia results from a shortage of red blood cells or haemoglobin within the cells. Aplastic anaemia, however, is associated with an insufficient number of all blood cells: red, white, and platelets.