Everyone Healthy Library
Autoimmune Hemolytic Anemia
Condition / disease reference page from the Everyone Healthy database.
Connected health information
Explore this condition in a clear order
Condition overview
Attributes
Commonalityis rare
Critical careis Yes
Incidenceis approximately 1 in 100,000 people
Linked signs and symptoms
12Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
2Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
2Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Medical emergencies
1Linked diagnostic tests and investigations
47These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- 2,3 Diphosphoglycerate (2,3-DPG) Concentration
- Acid Phosphatase Concentration
- Aspartate Aminotransferase (AST) Concentration
- Blood Uric Acid Concentration Test
- Cerebrospinal Fluid Examination Test
- Chloride Concentration (Blood)
- Cholesterol Concentration
- Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase)
- Coagulation Factor Assay (Blood Clotting Factors)
- Computerized Tomography (CT) Scan
- Electroencephalography (EEG)
- Eosinophils Count
- Erythrocyte Fragility Test (Osmotic Fragility, OF)
- erythrocyte Sedimentation Rate (ESR)
- Erythropoietin (Ep) Concentration
- Fecal Urobilinogen Concentration
- Ferritin Concentration
- Fibrinogen Concentration test
- Folic Acid (Folate) Concentration
- Free Erythrocyte Protoporphyrin (FEP) Concentration
- Glucose 6 Phosphate Dehydrogenase (G6PD) Concentration
- Glycosylated Hemoglobin (HbA1c) Concentration
- haptoglobin (Hp) concentration
- Heamatocrit (Hct)
- Hemoglobin (Hb) Concentration
- Iron Concentration
- Lactate Dehydrogenase Concentration
- Magnetic Resonance Imaging (MRI)
- Mean Corpuscular Hemoglobin Concentration (MCHC)
- Neurological Examinations
- Oxygen Saturation Test (Arterial Blood, SaO2)
- Parathyroid Hormone Concentration
- Partial Pressure of Arterial Carbon Dioxide (PCO2, PaCO2)
- Partial Pressure of Oxygen (PO2)
- Phosphate Concentration (PO4, Phosphorus)
- Platelet Count
- polymerase Chain Reaction (PCR) Test
- Potassium Concentration (K, Blood)
- Protein C (PC ANtigen)
- Protein Electrophoresis (Blood, Serum Protein)
- Protein S Concentration
- Pyruvate Kinase (PK) Concentration in RBC
- Red Blood Cell (RBC) Count
- Red Blood Cell Distribution Width (RDW) Test
- Reticulocyte Absolute Count
- Spinal Tap (lumbar Puncture)
- Urine Urobilinogen Concentration
Biological and test markers
43This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
24- 2,3 Diphosphoglycerate (2,3-DPG)Reference range exampleAdult ( > 16y): 10.5–14 µmol/gLinked diagnostic tests12, 3 Diphosphoglycerate (2
- Acid PhosphataseReference range exampleChild (0 - 16y), Male: 8.7–12.5 units/L; Adult ( > 16y), Male: 2.2–10.4 units/LLinked diagnostic tests1Acid Phosphatase Concentration
- Aspartate Aminotransferase (AST)Reference range exampleAdult ( > 16y), Female: 10–25 units/L; Adult ( > 16y), Male: 10–35 units/LLinked diagnostic tests1Aspartate Aminotransferase (AST) Concentration
- Beta GlobulinReference range exampleAll: 0.7–1.2 gm/dLLinked diagnostic tests1Protein Electrophoresis (Blood, Serum Protein)
- Chloride (Blood, Cl)Reference range exampleAdult ( > 16y): 97–106 mEq/L; Birth - 2wks: 94–106 mEq/LLinked diagnostic tests1Chloride Concentration (Blood)
- Cholesterol (Total)Reference range exampleInfant (0 - 1y): 75–180 mg/dL; Adult ( > 16y): 0–190 mg/dLLinked diagnostic tests1Cholesterol Concentration
- EosinophilsReference range exampleAdult ( > 16y): 0–3 %; 0–3 %Linked diagnostic tests3Differential White Blood Cell Count Tests, Eosinophil Differential Of Total WBC
- Erythrocyte Sedimentation RateReference range exampleAdult ( > 16y), Female: 0–20 mm/Hr; Adult ( > 16y), Male: 0–15 mm/HrLinked diagnostic tests1erythrocyte Sedimentation Rate (ESR)
- Erythropoietin (Ep)Reference range exampleAdult ( > 16y): 6–36 units/LLinked diagnostic tests1Erythropoietin (Ep) Concentration
- FerritinReference range exampleChild (0 - 16y): 7–140 µg/L; Adult ( > 16y), Female: 18–160 µg/LLinked diagnostic tests1Ferritin Concentration
- Free Erythrocyte Protoporphyrin (FEP)Reference range exampleAll: 16–37 µg/dLLinked diagnostic tests1Free Erythrocyte Protoporphyrin (FEP) Concentration
- Hemoglobin (Hb)Reference range exampleFemale: 78–100 gm/dL; Male: 76–100 gm/dLLinked diagnostic tests3Hemoglobin (Hb) Concentration, Mean Corpuscular Hemoglobin (MCH) Weight Test
- IronReference range exampleChild (0 - 16y): 50–120 µg/dL; Adult ( > 16y), Female: 50–150 µg/dLLinked diagnostic tests2Iron Concentration, Total Iron Binding Capacity (TIBC)
- Lactate Dehydrogenase (LDH)Reference range exampleInfant (0 - 1y): 120–250 units/L; Adult ( > 16y): 100–200 units/LLinked diagnostic tests1Lactate Dehydrogenase Concentration
- Percentage NaCl at which Hemolysis beginsReference range exampleAll: 0.5–0.6 %Linked diagnostic tests1Erythrocyte Fragility Test (Osmotic Fragility, OF)
- Percentage NaCl at which Hemolysis is completeReference range exampleAll: 0.3–0.35 %Linked diagnostic tests1Erythrocyte Fragility Test (Osmotic Fragility, OF)
- Phosphate (PO4, Phosphorus, P)Reference range exampleAdult ( > 16y): 2.5–4.5 mg/dL; Birth - 2wks: 4.3–9.2 mg/dLLinked diagnostic tests1Phosphate Concentration (PO4, Phosphorus)
- Potassium (K, Blood)AbbreviationKReference range exampleInfant (0 - 1y): 4.1–5.3 mEq/L; Child (0 - 16y): 3.4–4.7 mEq/LLinked diagnostic tests1Potassium Concentration (K, Blood)
- Red Blood Distribution Width (RDW)Reference range exampleAll: 11–14.5 %Linked diagnostic tests1Red Blood Cell Distribution Width (RDW) Test
- ReticulocytesReference range exampleAdult ( > 16y): 24–83 109/L; 0.5–1.5 %Linked diagnostic tests2Reticulocyte Absolute Count, Reticulocyte Count Percent Total RBC
- Segmented NeutrophilsReference range exampleAdult ( > 16y): 50–62 %; Adult ( > 16y): 2,500–8,000 mm3Linked diagnostic tests2Differential White Blood Cell Count Tests, Neutrophil Absolute Count
- Uric Acid, BloodReference range exampleAdult ( > 16y), Female: 2.5–7 mg/dL; Adult ( > 16y), Male: 4–8 mg/dLLinked diagnostic tests1Blood Uric Acid Concentration Test
- Urobilinogen (Stools)Reference range exampleAll: 50–300 mg/24hrsLinked diagnostic tests1Fecal Urobilinogen Concentration
- Urobilinogen (Urine)Reference range exampleAll: 0.1–1 mg/dLLinked diagnostic tests1Urine Urobilinogen Concentration
Often decreased
19- Alpha-1-Globulin (Blood, Serum)Reference range exampleAll: 0.1–0.3 gm/dLLinked diagnostic tests1Protein Electrophoresis (Blood, Serum Protein)
- Alpha-2-Globulin (Blood, Serum)Reference range exampleAll: 0.6–1 gm/dLLinked diagnostic tests1Protein Electrophoresis (Blood, Serum Protein)
- CholinesteraseReference range exampleAll: 6–19 U/mLLinked diagnostic tests1Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase)
- Factor VIII (Antihemophilic Globulin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 55–145 %Linked diagnostic tests1Coagulation Factor Assay (Blood Clotting Factors)
- FibrinogenReference range exampleAdult ( > 16y): 150–400 mg/dLLinked diagnostic tests1Fibrinogen Concentration test
- Folic Acid (Folate)Reference range exampleInfant (0 - 1y): 14–51 ng/mL; Child (0 - 16y): 5–21 ng/mLLinked diagnostic tests1Folic Acid (Folate) Concentration
- Glucose 6 Phosphate Dehydrogenase (G6PD)Reference range exampleAdult ( > 16y): 10.1–18.5 U/gHb; Birth - 2wks: 12–23 U/gHbLinked diagnostic tests1Glucose 6 Phosphate Dehydrogenase (G6PD) Concentration
- haptoglobin (Hp)Reference range example45–200 mg/dLLinked diagnostic tests1haptoglobin (Hp) concentration
- Hemoglobin (Hb)
- Oxygen Saturation (Arterial Blood, SaO2)Reference range exampleChild (0 - 16y): 95–100 %; Newborn (0 - 1month): 40–90 %Linked diagnostic tests1Oxygen Saturation Test (Arterial Blood, SaO2)
- Parathyroid hormone (PTH, Parathormone)Reference range exampleAdult ( > 16y): 10–62 pg/mLLinked diagnostic tests1Parathyroid Hormone Concentration
- Partial Pressure of Arterial Carbon Dioxide (PaCO2)Reference range exampleAll: 35–45 mm HgLinked diagnostic tests1Partial Pressure of Arterial Carbon Dioxide (PCO2, PaCO2)
- Partial Pressure of Arterial Oxygen (PaO2)Reference range exampleChild (0 - 16y): 80–100 mm Hg; Newborn (0 - 1month): 60–70 mm HgLinked diagnostic tests1Partial Pressure of Oxygen (PO2)
- PlateletsReference range exampleChild (0 - 16y): 150–450 109/L; Adult ( > 16y): 135–380 109/LLinked diagnostic tests1Platelet Count
- Protein CReference range exampleAdult ( > 16y): 70–150 %Linked diagnostic tests1Protein C (PC ANtigen)
- Protein SReference range exampleAdult ( > 16y), Female: 50–120 %; Adult ( > 16y), Male: 55–120 %Linked diagnostic tests1Protein S Concentration
- Pyruvate Kinase (PK)Reference range example2.75–8.7 µmol/gLinked diagnostic tests1Pyruvate Kinase (PK) Concentration in RBC
- RBC MassReference range exampleFemale: 36–48 %; Male: 42–52 %Linked diagnostic tests1Heamatocrit (Hct)
- Red Blood Cells (RBC)Reference range exampleAdult ( > 16y), Female: 3.6–5 106/mm3; Adult ( > 16y), Male: 4.2–5.4 106/mm3Linked diagnostic tests1Red Blood Cell (RBC) Count
Other associated markers
0No markers in this group.
Introduction / full article
Autoimmune Hemolytic Anemia
Autoimmune Hemolytic Anemia
Autoimmune haemolytic anaemia (abbreviated to AIHA) actually refers to a group of disorders characterised by a defect of the immune system, wherein autoantibodies attack and destroy red blood cells as though they were harmful foreign substances in the bloodstream.
AIHA is an uncommon group of disorders, and can affect individuals of an age, although women tend to be at greater risk. In approximately half of cases, the cause of AIHA remains unidentified. The disorders are also known to accompany other disorders, as well as the use of certain drugs. Destruction of the red blood cells can occur spontaneously, or over a longer period of time.