Everyone Healthy Library
Fatty Liver
Condition / disease reference page from the Everyone Healthy database.
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Connected health information
Explore this condition in a clear order
Linked signs and symptoms
2Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
0No linked drugs are listed yet.
Treatments, therapies and supportive options
24Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Medical therapy
3Lifestyle changes
6Alternative and complementary therapies
5Alternative medicine
5- Celandine (Ukrain, Chelidonium Majus)Weakly Against(Very Low Evidence)
- CiticolineEvidence: 2
- Indian Snakeroot (Rauvolfia, Rawolfia Serpentina)No Recommendation(Very Low Evidence)
- Licorice (Glycyrrhiza Glabra, Gan Cao)No Recommendation(Very Low Evidence)
- Tumeric (Curcuma longa)No Recommendation(Very Low Evidence)
Alternative therapies
1Amino acids
1Linked diagnostic tests and investigations
42These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Acid Phosphatase Concentration
- Activated Coagulation Time (ACT)
- Activated Partial Thromboplastin Time (APTT)
- Alpha-1 Antitrypsin (AAT) Concentration
- Antithrombin 111 (AT-111) Activity Test
- Aspartate Aminotransferase (AST) Concentration
- Blood Urea Nitrogen Tests
- Blood Uric Acid Concentration Test
- Coagulation Factor Assay (Blood Clotting Factors)
- Creatine Kinase Concentration
- D-Dimer Blood Test
- Fibrin Degradation Products (FDPs, Fibrin Split Products, FSPs, Fibrin Breakdown Products, Fbps)
- Fibrin Monomers Test
- Fibrinogen Concentration test
- Folic Acid (Folate) Concentration
- Gamma-Glutamyltransferase (GGT) Concentration
- Glucose Tolerance Test (GTT, OGTT, 120 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 160 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 30 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 60 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, Fasting Glucose)
- Glucose Tolerance Test for Gestational Diabetes (1 Hour After Glucose Load)
- Glucose Tolerance Test for Gestational Diabetes (Fasting Glucose Value)
- Glucose, Blood (Post Prandiol Blood Glucose Test, 2 Hour Post Meal Blood Glucose)
- haptoglobin (Hp) concentration
- HPV DNA Test
- Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Lactate Dehydrogenase Concentration
- Lactic Acid Concentration
- lipase concentration
- Low Density Lipoprotein (LDL) Concentration
- Mean Corpuscular Volume (MCV)
- Osmolality, Blood (Serum Osmolality)
- Phenylketonuria Test
- Potassium Concentration (K, Blood)
- Protein Electrophoresis (Blood, Serum Protein)
- Prothrombin Time (PT)
- scratch-N-Sniff Odor Tests
- Thrombin Time
- Triiodothyronine (Free T3) Concentration
- Urine Crystal Concentration
- Urine Sodium Quantitative (24hr)
Biological markers/agents
40This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
22- Acid PhosphataseReference range exampleChild (0 - 16y), Male: 8.7–12.5 units/L; Adult ( > 16y), Male: 2.2–10.4 units/LLinked diagnostic testsAcid Phosphatase Concentration
- Aspartate Aminotransferase (AST)Reference range exampleAdult ( > 16y), Female: 10–25 units/L; Adult ( > 16y), Male: 10–35 units/LLinked diagnostic testsAspartate Aminotransferase (AST) Concentration
- Calcium Oxalate Crystals (Urine)Reference range exampleAll: 0–1 Not PresentLinked diagnostic testsUrine Crystal Concentration
- Coagulation Bleeding TimeReference range exampleAdult ( > 16y): 65–110 secondsLinked diagnostic testsActivated Coagulation Time (ACT)
- D-DimerReference range exampleAdult ( > 16y): 0–240 µg/LLinked diagnostic testsD-Dimer Blood Test
- Fibrin MonomersReference range example0–10,000 µg/LLinked diagnostic testsFibrin Monomers Test
- Fibrin Split ProductsReference range exampleAll: 0–1 mg/dLLinked diagnostic testsFibrin Degradation Products (FDPs, Fibrin Split Products
- Gamma Globulin (Blood, Serum)Reference range exampleAll: 0.8–1.7 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Gamma-Glutamyltransferase (GGT)Reference range exampleAdult ( > 16y), Female: 6–30 units/L; Adult ( > 16y), Male: 6–38 units/LLinked diagnostic testsGamma-Glutamyltransferase (GGT) Concentration
- Human Placental Lactogen (HPL, Pregnancy Weaks 25 to 30)Reference range exampleAdult ( > 16y), Female: 2,300–6,100 µg/LLinked diagnostic testsHuman Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (hPL, Pregnancy Weaks 31 to 35)Reference range exampleAdult ( > 16y), Female: 3,800–8,800 µg/LLinked diagnostic testsHuman Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (hPL, Pregnancy Weaks 36 to 40)Reference range exampleAdult ( > 16y), Female: 4,900–8,600 µg/LLinked diagnostic testsHuman Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (HPL, Pregnancy Weaks 5 to 25)Reference range exampleAdult ( > 16y), Female: 0–4,500 µg/LLinked diagnostic testsHuman Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Lactate Dehydrogenase (LDH)Reference range exampleInfant (0 - 1y): 120–250 units/L; Adult ( > 16y): 100–200 units/LLinked diagnostic testsLactate Dehydrogenase Concentration
- Lactic Acid (Venous Blood)Reference range exampleAll: 0.5–2.2 mEq/LLinked diagnostic testsLactic Acid Concentration
- LipaseReference range exampleAdult ( > 16y): 10–140 units/LLinked diagnostic testslipase concentration
- Low Density Lipoprotein (LDL)Reference range exampleAdult ( > 16y): 0–125 mg/dL; 6y - 16y: 0–100 mg/dLLinked diagnostic testsLow Density Lipoprotein (LDL) Concentration
- Osmolality, Blood (Serum Osmolality)Reference range exampleChild (0 - 16y): 274–290 mOsm/kg; Birth - 2wks: 265–285 mOsm/kgLinked diagnostic testsOsmolality, Blood (Serum Osmolality)
- PhenylalanineReference range exampleAdult ( > 16y): 0–16 mg/24hrs; Child (5 - 12y): 4–16.5 mg/24hrsLinked diagnostic testsPhenylketonuria Test
- Plasma thromboplastin antecedentReference range exampleAdult ( > 16y): 20–35 secondsLinked diagnostic testsActivated Partial Thromboplastin Time (APTT)
- Red Blood Cell (RBC) VolumeReference range example76–100 fLLinked diagnostic testsMean Corpuscular Volume (MCV)
- Thrombin TimeReference range exampleAdult ( > 16y): 10–20 secondsLinked diagnostic testsThrombin Time
Often decreased
18- Alpha-1 Antintrypsin (AAT)Reference range exampleAdult ( > 16y): 90–215 mg/dLLinked diagnostic testsAlpha-1 Antitrypsin (AAT) Concentration
- Antithrombin 111 (AT-111)Reference range exampleAdult ( > 16y): 90–110 %Linked diagnostic testsAntithrombin 111 (AT-111) Activity Test
- Blood Urea NitrogenReference range exampleAdult ( > 16y): 6–18 mg/dL; Child (< 10y): 5–15 mg/dLLinked diagnostic testsBlood Urea Nitrogen Tests
- Creatine Kinase (CK)Reference range exampleAdult ( > 16y), Female: 35–150 units/L; Adult ( > 16y), Male: 40–170 units/LLinked diagnostic testsCreatine Kinase Concentration
- Factor II (Prothrombin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 80–120 %; Adult ( > 16y): 80–120 %Linked diagnostic testsCoagulation Factor Assay (Blood CLotting Factors, Coagulation Factor Assay (Blood Clotting Factors)
- Factor IX (Christmas Factor, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 60–140 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Factor V (Labile Factor, Proaccelerin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 50–150 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Factor X (Stuart Prower Factor, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 45–155 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Factor XI (Plasma Thromboplastin Antecedent, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 65–135 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Factor XII (Hageman Factor, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 50–150 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- FibrinogenReference range exampleAdult ( > 16y): 150–400 mg/dLLinked diagnostic testsFibrinogen Concentration test
- Folic Acid (Folate)Reference range exampleInfant (0 - 1y): 14–51 ng/mL; Child (0 - 16y): 5–21 ng/mLLinked diagnostic testsFolic Acid (Folate) Concentration
- Glucose (Blood)Reference range exampleInfant (0 - 1y): 3–6.1 mmol/L; Adult ( > 16y): 0–6.1 mmol/LLinked diagnostic testsfasting Blood Glucose Test, Glucose Tolerance Test (GTT
- haptoglobin (Hp)Reference range example45–200 mg/dLLinked diagnostic testshaptoglobin (Hp) concentration
- Potassium (K, Blood)AbbreviationKReference range exampleInfant (0 - 1y): 4.1–5.3 mEq/L; Child (0 - 16y): 3.4–4.7 mEq/LLinked diagnostic testsPotassium Concentration (K, Blood)
- Triiodothyronine (Free T3)Reference range example2.7–4.9 pg/mLLinked diagnostic testsTriiodothyronine (Free T3) Concentration
- Uric Acid, BloodReference range exampleAdult ( > 16y), Female: 2.5–7 mg/dL; Adult ( > 16y), Male: 4–8 mg/dLLinked diagnostic testsBlood Uric Acid Concentration Test
- Urine SodiumReference range exampleChild (0 - 16y): 41–115 mmol/day; Adult ( > 16y): 40–220 mmol/dayLinked diagnostic testsUrine Sodium Quantitative (24hr)
Introduction / full article
Fatty Liver
Fatty Liver
Overview
This is the effect of the accumulation of different types of fats in the liver. There should be balance between the fatty acids that enter the liver with the amount that is excreted out, but this cycle is not followed when there is fatty liver. The most common cause of fatty liver is excessive alcohol intake. However, people who do not drink alcohol may also be at risk, especially people with diabetes or obesity. Symptoms may include fatigue, excessive weight loss, headache, and difficulty concentrating or making sound judgement.
Efficacy of Alternative and Other Treatments According to GRADE* Ranking
Turmeric [1, 10, 11, 12, 13, 14, 15]
Note: Please note, this management does not treat the condition itself. It is proposed only as weak supportive symptomatic support, and even then has insufficient evidence to back up this claim at present.
Recommendation: No recommendation. There is insufficient evidence to support claims that turmeric can help in the treatment of liver disease. More research is needed.
Grade of Evidence: Very low quality of evidence
Licorice (Glycyrrhiza glabra) [1, 6, 7, 8, 9]
Note: Please note, this management does not treat the condition itself. It may mildly help with some symptoms, and even then has insufficient evidence to back up this claim at present. Licorice has potentially harmful side effects in people with high blood pressure, liver disease, or kidney disease.
Recommendation: No recommendation. There is insufficient evidence to support claims that licorice helps treat some symptoms of fatty liver. More research is needed.
Grade of Evidence: Very low quality of evidence
Indian Snakeroot (Rauwolfia serpentina) [1, 4, 5]
Note: Please note, this management does not treat the condition itself. It may mildly help with some symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: No recommendation. There is insufficient evidence to support claims that Indian Snakeroot helps to treat fatty liver in any way.
Grade of Evidence: Very low quality of evidence
Celandine (Ukrain, Chelidonium majus) [1, 2, 3]
Note: Please note, this management does not treat the condition itself. It is proposed only as weak supportive symptomatic support, and even then has insufficient evidence to back up this claim at present.
Recommendation: Weakly against. There is insufficient evidence that Celandine helps to cure or treat liver fibrosis. In addition, the plant is mildly poisonous to humans. It may cause hepatitis as well as symptoms of pain, nausea, thirst, and fever.
Grade of Evidence: Very low quality of evidence
Neural Therapy
Note: Please note, this management does not treat the condition itself. It is proposed only as weak supportive symptomatic support, and even then has insufficient evidence to back up this claim at present.
Recommendation: No recommendation. There is insufficient evidence to show that Neural Therapy helps in treating fatty liver in any way.
Grade of Evidence: Very low quality of evidence
* GRADE Working Group: www.gradeworkinggroup.org
Summary References
Treatments
- Ades T, Alteri R, Gansler T, Yeargin P. Complete Guide to Complementary & Alternative Cancer Therapies. American Cancer Society; 2009.
- ABC Homeopathy: Chelidonium majus.
- Natural Standard: Greater celandine.
- American Cancer Society: Indian snakeroot.
- Merck Source / Dorland’s entry.
- Winston D, Maimes S. Adaptogens: Herbs for Strength, Stamina, and Stress Relief. Healing Arts Press; 2007.
- PubMed PMID: 15190039.
- NCCAM: Licorice root.
- MedlinePlus: Licorice.
- American Cancer Society: Turmeric.
- MedlinePlus: Turmeric.
- NCCAM: Turmeric.
- BBC News: Turmeric health article.
- Mirror: Curry / turmeric health article.
- ClinicalTrials.gov: Turmeric search results.