Everyone Healthy Library
Multiple Myeloma
Condition / disease reference page from the Everyone Healthy database.
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Connected health information
Explore this condition in a clear order
Condition overview
Attributes
Incidenceis approximately 1 in 25,000 people
Linked signs and symptoms
8Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
7Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
11Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Surgery
2Medical therapy
4Alternative and complementary therapies
1Alternative medicine
1Linked diagnostic tests and investigations
35These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Acid Phosphatase Concentration
- Angiotensin Converting Enzyme (ACE) Concentration
- Anion Gap
- Blood Human Chorionic Gonadotropin (hCG) Test
- Blood Tests
- Blood Uric Acid Concentration Test
- Bone Marrow Test
- Calcium Concentration (Blood, Total)
- Chloride Concentration (Blood)
- Coagulation Factor Assay (Blood Clotting Factors)
- Computerized Tomography (CT) Scan
- Creatinine Concentration (Blood, Serum Creatinine)
- erythrocyte Sedimentation Rate (ESR)
- Fetal Hemoglobin (Hemoglobin F, HbF) Concentration
- Fibrinogen Concentration test
- Heamatocrit (Hct)
- Hemoglobin (Hb) Concentration
- Low Density Lipoprotein (LDL) Concentration
- Lymphocyte Immunophenotyping
- Lymphocytes Count
- Magnesium Concentration (Mg, Blood)
- magnetic Resonance Angiogram (MRA)
- Monocyte Absolute Count
- Phosphate Concentration (PO4, Phosphorus)
- Platelet Aggregation Test
- Platelet Count
- Potassium Sensitivity Test
- Protein Electrophoresis (Blood, Serum Protein)
- Red Blood Cell (RBC) Count
- Urine Albumin 24hr test
- Urine Amino Acid Concentration
- Urine Hydroxyproline Concentration
- Urine Osmolality
- Urine Test
- White Blood Cell (WBC) Count
Biological markers/agents
60This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
49- 1 Methylhistidine (Urine)Reference range exampleChild (0 - 16y): 450–3,200 µmol/L; Adult ( > 16y): 700–8,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- 3 Methylhistidine (Urine)Reference range exampleChild (0 - 16y): 420–1,400 µmol/L; Adult ( > 16y): 650–3,300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Acid PhosphataseReference range exampleChild (0 - 16y), Male: 8.7–12.5 units/L; Adult ( > 16y), Male: 2.2–10.4 units/LLinked diagnostic testsAcid Phosphatase Concentration
- Alanine (Urine)Reference range exampleAdult ( > 16y): 1,500–7,000 µmol/L; Child (< 10y): 600–2,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alpha Amino N Buryric Acid (Urine)Reference range exampleAdult ( > 16y): 0–350 µmol/L; Child (< 10y): 80–300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alpha Aminoadipic Acid (Urine)Reference range exampleAdult ( > 16y): 0–1,700 µmol/L; Child (< 10y): 240–800 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Angiotensin Converting Enzyme (ACE)Reference range exampleAll: 0–45 units/LLinked diagnostic testsAngiotensin Converting Enzyme (ACE) Concentration
- Arginine (Urine)Reference range exampleChild (0 - 16y): 120–260 µmol/L; Adult ( > 16y): 140–650 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Asparagine (Urine)Reference range exampleChild (0 - 16y): 160–420 µmol/L; Adult ( > 16y): 350–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Aspartic Acid (Urine)Reference range exampleChild (0 - 16y): 110–270 µmol/L; Adult ( > 16y): 150–900 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Calcium (Blood, Total)Reference range exampleAdult ( > 16y): 8.5–10.4 mg/dL; Birth - 2wks: 7.6–10.3 mg/dLLinked diagnostic testsCalcium Concentration (Blood, Total)
- Carnosine (Urine)Reference range exampleChild (0 - 16y): 350–2,500 µmol/L; Adult ( > 16y): 170–1,300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Chloride (Blood, Cl)Reference range exampleAdult ( > 16y): 97–106 mEq/L; Birth - 2wks: 94–106 mEq/LLinked diagnostic testsChloride Concentration (Blood)
- Citrulline (Urine)Reference range exampleChild (0 - 16y): 0–140 µmol/L; Adult ( > 16y): 0–100 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Creatinine (Blood)Reference range exampleInfant (0 - 1y): 0.1–0.4 mg/dL; Adult ( > 16y), Female: 0.6–1.2 mg/dLLinked diagnostic testsCreatinine Concentration (Blood, Serum Creatinine)
- Cystine (Urine)Reference range exampleChild (0 - 16y): 120–540 µmol/L; Adult ( > 16y): 300–1,200 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Erythrocyte Sedimentation RateReference range exampleAdult ( > 16y), Female: 0–20 mm/Hr; Adult ( > 16y), Male: 0–15 mm/HrLinked diagnostic testserythrocyte Sedimentation Rate (ESR)
- Factor VIII (Antihemophilic Globulin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 55–145 %Linked diagnostic testsCoagulation Factor Assay (Blood Clotting Factors)
- Fetal Hemoglobin (Hemoglobin F, HbF)Reference range exampleAdult ( > 16y): 0–2.1 %; Birth - 2wks: 56–90 %Linked diagnostic testsFetal Hemoglobin (Hemoglobin F, HbF) Concentration
- FibrinogenReference range exampleAdult ( > 16y): 150–400 mg/dLLinked diagnostic testsFibrinogen Concentration test
- Gamma Globulin (Blood, Serum)Reference range exampleAll: 0.8–1.7 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Glutamic Acid (Urine)Reference range exampleChild (0 - 16y): 135–240 µmol/L; Adult ( > 16y): 300–1,100 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Glutamine (Urine)Reference range exampleChild (0 - 16y): 1,600–4,000 µmol/L; Adult ( > 16y): 3,000–10,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Glycine (Urine)Reference range exampleChild (0 - 16y): 2,000–8,500 µmol/L; Adult ( > 16y): 8,000–25,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Histidine (Urine)Reference range exampleChild (0 - 16y): 500–7,300 µmol/L; Adult ( > 16y): 5,000–16,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Human Chorionic Gonadotropin (Blood hCG)Reference range exampleAdult ( > 16y): 0–5 units/LLinked diagnostic testsBlood Human Chorionic Gonadotropin (hCG) Test
- Hydroxyproline (Urine Excretion Rate)Reference range exampleAdult ( > 16y): 14–45 mg/24hrs; Adult ( > 16y), Female: 0.4–2.9 mg/2hrsLinked diagnostic testsUrine Amino Acid Concentration, Urine Hydroxyproline Concentration
- Isoleucine (Urine)Reference range exampleChild (0 - 16y): 40–150 µmol/L; Child (0 - 16y): 100–250 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Low Density Lipoprotein (LDL)Reference range exampleAdult ( > 16y): 0–125 mg/dL; 6y - 16y: 0–100 mg/dLLinked diagnostic testsLow Density Lipoprotein (LDL) Concentration
- LymphocytesReference range exampleAdult ( > 16y): 25–40 %; 700–3,500 cells/mm3Linked diagnostic testsDifferential White Blood Cell Count Tests, Lymphocytes Count
- Lysine (Urine)Reference range exampleChild (0 - 16y): 200–1,500 µmol/L; Adult ( > 16y): 300–3,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Magnesium (Mg, Blood)Reference range exampleAdult ( > 16y): 1.3–2.6 mEq/L; Birth - 2wks: 1.4–2.2 mEq/LLinked diagnostic testsMagnesium Concentration (Mg, Blood)
- Methionine (Urine)Reference range exampleChild (0 - 16y): 70–220 µmol/L; Adult ( > 16y): 55–320 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- MonocytesReference range exampleAdult ( > 16y): 3–7 %; 0.1–0.5 million/mLLinked diagnostic testsDifferential White Blood Cell Count Tests, Monocyte Absolute Count
- Ornithine (Urine)Reference range exampleChild (0 - 16y): 40–165 µmol/L; Adult ( > 16y): 50–800 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Phenylalanine (Urine)Reference range exampleChild (0 - 16y): 200–600 µmol/L; Adult ( > 16y): 400–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Phosphate (PO4, Phosphorus, P)Reference range exampleAdult ( > 16y): 2.5–4.5 mg/dL; Birth - 2wks: 4.3–9.2 mg/dLLinked diagnostic testsPhosphate Concentration (PO4, Phosphorus)
- Phosphoethanolamine (Urine)Reference range exampleChild (0 - 16y): 250–670 µmol/L; Adult ( > 16y): 200–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Phosphoserine (Urine)Reference range exampleChild (0 - 16y): 150–350 µmol/L; Child (0 - 16y): 1,000–2,200 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Proline (Urine)Reference range exampleChild (0 - 16y): 0–1 Not PresentLinked diagnostic testsUrine Amino Acid Concentration
- Protein, Total (Blood, Serum)Reference range exampleInfant (0 - 1y): 6–6.7 gm/dL; Child (0 - 16y): 6.1–8.2 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Serine (Urine)Reference range exampleChild (0 - 16y): 1,000–2,200 µmol/L; Adult ( > 16y): 2,000–7,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Taurine (Urine)Reference range exampleChild (0 - 16y): 600–9,800 µmol/L; Adult ( > 16y): 2,700–13,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Threonine (Urine)Reference range exampleChild (0 - 16y): 250–1,000 µmol/L; Adult ( > 16y): 900–3,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Tyrosine (Urine)Reference range exampleChild (0 - 16y): 300–850 µmol/L; Adult ( > 16y): 400–1,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Uric Acid, BloodReference range exampleAdult ( > 16y), Female: 2.5–7 mg/dL; Adult ( > 16y), Male: 4–8 mg/dLLinked diagnostic testsBlood Uric Acid Concentration Test
- Urine AlbuminReference range exampleAdult ( > 16y), Female: 30–105 mg/dL; Adult ( > 16y), Male: 10–145 mg/dLLinked diagnostic testsUrine Albumin 24hr test
- Valine (Urine)Reference range exampleChild (0 - 16y): 200–400 µmol/L; Adult ( > 16y): 200–750 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- White Blood Cell (WBC)Reference range exampleAdult ( > 16y): 4.5–10.5 million/mL; Adult ( > 16y): 3.2–10 million/mLLinked diagnostic testsWhite Blood Cell (WBC) Count
Often decreased
11- Anion Gap (Excluding Potassium)Reference range exampleAll: 12–20 mEq/L; All: 8–16 mEq/LLinked diagnostic testsAnion Gap
- Anion Gap (Including Potassium)Reference range exampleAll: 12–20 mEq/LLinked diagnostic testsAnion Gap
- B Cells (CD19 Percentage)Reference range exampleAll: 3–25 %Linked diagnostic testsLymphocyte Immunophenotyping
- CD4 to CD8 RatioReference range exampleAll: 1–5 RatioLinked diagnostic testsLymphocyte Immunophenotyping
- Complete Platelet Aggregation in Response to Collagen, Thrombin, RistocetinReference range exampleAll: 0–1 PresentLinked diagnostic testsPlatelet Aggregation Test
- Hemoglobin (Hb)Reference range exampleFemale: 78–100 gm/dL; Male: 76–100 gm/dLLinked diagnostic testsHemoglobin (Hb) Concentration, Mean Corpuscular Hemoglobin (MCH) Weight Test
- PlateletsReference range exampleChild (0 - 16y): 150–450 109/L; Adult ( > 16y): 135–380 109/LLinked diagnostic testsPlatelet Count
- RBC MassReference range exampleFemale: 36–48 %; Male: 42–52 %Linked diagnostic testsHeamatocrit (Hct)
- Red Blood Cells (RBC)Reference range exampleAdult ( > 16y), Female: 3.6–5 106/mm3; Adult ( > 16y), Male: 4.2–5.4 106/mm3Linked diagnostic testsRed Blood Cell (RBC) Count
- UrineReference range exampleAdult ( > 16y): 4.5–7.5; Child (0 - 16y): 500–1,400 mLLinked diagnostic testsUrine Colour, Urine Creatinine Concentration
- Urine OsmolalityReference range exampleAdult ( > 16y): 250–950 mOsm/kgLinked diagnostic testsUrine Osmolality
Introduction / full article
Multiple Myeloma
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Vitae Elixxir[1, 2, 3]:
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present. Warning: Possible side effects of Vitae Elixxir include diarrhoea, pain, and a general worsening of existing symptoms.
Recommendation: No recommendation (Available evidence does not support claims that vitae elixir helps to treat multiple myeloma)
Grade of Evidence: very low quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://www.annieappleseedproject.org/vitaeelixxir.html
3. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/vitae-elixxir