Everyone Healthy Library
Polycystic Kidney Disease
Condition / disease reference page from the Everyone Healthy database.
! Seek urgent medical care if warning signs appear
Some health conditions or symptoms can become urgent. Use this page for education, but seek help quickly if warning signs are present.
Get urgent medical care now if there is any severe, sudden, rapidly worsening or worrying symptom, especially:
- chest pain, pressure or pain spreading to the arm, jaw or back
- trouble breathing, blue lips, severe wheeze or choking
- stroke-like symptoms such as face drooping, arm weakness or speech trouble
- collapse, fainting, seizure, confusion or extreme drowsiness
- severe bleeding, black stools, vomiting blood or major injury
- severe allergic reaction, swelling of the face/throat or widespread rash with breathing trouble
- severe abdominal pain, severe headache, stiff neck or sudden vision change
- signs of severe dehydration, sepsis, high fever with worsening illness, or symptoms in a baby/young child that concern you
Connected health information
Explore this condition in a clear order
Condition overview
Attributes
Commonalityis rare
Incidenceis approximately 1 in 800 people
Linked signs and symptoms
19Each sign/symptom opens its own page and links back to related conditions.
- Blood in Urine (Hematuria)
- Blood Pressure High (Hypertension)
- Cramps Abdomen
- Digits Pallor
- Drowsiness
- Fatigue
- Heart Murmur (Detected by Stethoscope)
- Liver Enlarged Or Tender
- Nausea
- Pain Abdominal
- Pain Back
- Pain During Menstruation (Dysmenorrhoea)
- Pain Joint (Arthralgia)
- Pain Side (Flank)
- Skin Dry
- Swelling (Oedema, Edema)
- Urination Increase At Night (Nocturia)
- Urination of Large Volume of Urine (Polyuria)
- Urine Contains Abnormal Protein (Proteinuria)
Linked drugs / medications
0No linked drugs are listed yet.
Treatments, therapies and supportive options
6Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Surgery
1Medical therapy
2Alternative and complementary therapies
1Alternative medicine
1Linked diagnostic tests and investigations
19These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Acid Phosphatase Concentration
- Apolipoprotein A Concentration
- Apolipoprotein B Concentration
- Blood Uric Acid Concentration Test
- Calcitonin (Thyrocalcitonin) Concentration
- Chloride Concentration (Blood)
- Creatinine Clearance (CrCl)
- Fetal Nuchal Translucency (FNT on Ultrasound)
- Fibrin Degradation Products (FDPs, Fibrin Split Products, FSPs, Fibrin Breakdown Products, Fbps)
- Folic Acid (Folate) Concentration
- Protein S Concentration
- Sodium Concentration (Na, Blood)
- Triglyceride (TGs) Concentration
- Triiodothyronine (Free T3) Concentration
- Triiodothyronine (Total T3) Concentration
- Triiodothyronine Uptake Test
- Urine Chloride Concentration
- Urine Haemologlobin (Hb) Concentration
- Urine Red Blood Cells Concentration
Biological markers/agents
19This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
11- Acid PhosphataseReference range exampleChild (0 - 16y), Male: 8.7–12.5 units/L; Adult ( > 16y), Male: 2.2–10.4 units/LLinked diagnostic testsAcid Phosphatase Concentration
- Apolipoprotein B (Apo B)Reference range exampleAdult ( > 16y), Female: 47–115 mg/dL; Adult ( > 16y), Male: 52–120 mg/dLLinked diagnostic testsApolipoprotein B Concentration
- Calcitonin (CT)Reference range exampleAll, Female: 0–14 pg/mL; All, Male: 0–19 pg/mLLinked diagnostic testsCalcitonin (Thyrocalcitonin) Concentration
- Chloride (Blood, Cl)Reference range exampleAdult ( > 16y): 97–106 mEq/L; Birth - 2wks: 94–106 mEq/LLinked diagnostic testsChloride Concentration (Blood)
- Fetal Nuchal Thickness on Ultrasound (Pregnancy Weeks 10 to 14)Reference range exampleAdult ( > 16y), Female: 2.18–2.5Linked diagnostic testsFetal Nuchal Translucency (FNT on Ultrasound)
- Fibrin Split ProductsReference range exampleAll: 0–1 mg/dLLinked diagnostic testsFibrin Degradation Products (FDPs, Fibrin Split Products
- TriglyceridesReference range exampleAdult ( > 16y), Female: 32–137 mg/dL; Adult ( > 16y), Male: 35–155 mg/dLLinked diagnostic testsTriglyceride (TG's) Concentration, Triglyceride (TGs) Concentration
- Triiodothyronine Uptake PercentageReference range exampleAll: 25–38 %Linked diagnostic testsTriiodothyronine Uptake Test
- Uric Acid, BloodReference range exampleAdult ( > 16y), Female: 2.5–7 mg/dL; Adult ( > 16y), Male: 4–8 mg/dLLinked diagnostic testsBlood Uric Acid Concentration Test
- Urine Haemoglobin (Hb)Reference range exampleAdult ( > 16y): 0–0.02 mg/dLLinked diagnostic testsUrine Haemologlobin (Hb) Concentration
- Urine Red Blood CellsReference range exampleAdult ( > 16y): 0–2 /hpfLinked diagnostic testsUrine Red Blood Cells Concentration
Often decreased
8- Apolipoprotein A (Apo A)Reference range exampleAdult ( > 16y), Female: 85–170 mg/dL; Adult ( > 16y), Male: 77–155 mg/dLLinked diagnostic testsApolipoprotein A Concentration
- Creatinine Clearance RateReference range exampleAdult ( > 16y), Female: 87–110 ml/minute; Adult ( > 16y), Male: 100–140 ml/minuteLinked diagnostic testsCreatinine Clearance (CrCl)
- Folic Acid (Folate)Reference range exampleInfant (0 - 1y): 14–51 ng/mL; Child (0 - 16y): 5–21 ng/mLLinked diagnostic testsFolic Acid (Folate) Concentration
- Protein SReference range exampleAdult ( > 16y), Female: 50–120 %; Adult ( > 16y), Male: 55–120 %Linked diagnostic testsProtein S Concentration
- Sodium (Na, Blood)Reference range exampleInfant (0 - 1y): 134–150 mEq/L; Child (0 - 16y): 136–145 mEq/LLinked diagnostic testsSodium Concentration (Na, Blood)
- Triiodothyronine (Free T3)Reference range example2.7–4.9 pg/mLLinked diagnostic testsTriiodothyronine (Free T3) Concentration
- Triiodothyronine (Total T3)Reference range exampleInfant (0 - 1y): 1.1–2.43 ng/mL; Adult ( > 16y): 1–2.1 ng/mLLinked diagnostic testsTriiodothyronine (Total T3) Concentration
- Urine ChlorideReference range exampleInfant (0 - 1y): 2–10 mmol/day; Child (0 - 16y): 15–14 mmol/dayLinked diagnostic testsUrine Chloride Concentration
Introduction / full article
Polycystic Kidney Disease
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
St John's Wort (Goatweed, tipton weed, Hypericum Perforatum) [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (Available evidence does not support claims that St Johns Wort can help to treat kidney disease)
Grade of Evidence: low quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/st-johns-wort
3. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-stjohnswort.html
4. http://www.ncbi.nlm.nih.gov/pubmed/18843608
5. http://www.ncbi.nlm.nih.gov/pubmed/11939866
6. http://nccam.nih.gov/health/stjohnswort/ataglance.htm
7. http://nccam.nih.gov/health/stjohnswort/sjw-and-depression.htm
8. http://www.nimh.nih.gov/health/publications/depression/how-is-depression-detected-and-treated.shtml
9. http://www.ncbi.nlm.nih.gov/pubmed/11939872
10. http://www.ncbi.nlm.nih.gov/pubmed/12132963
11. http://www.ncbi.nlm.nih.gov/pubmed/16423519
12. http://jama.ama-assn.org/cgi/content/full/299/22/2633