Euthyroid Goiter

Connected health information

Explore this condition in a clear order

1. Attributes 2. Signs & symptoms 3. Drugs / medications 4. Treatments by type 5. Further tests / investigations 6. Biological / test markers

Linked signs and symptoms

9

Each sign/symptom opens its own page and links back to related conditions.

Linked drugs / medications

1

Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.

Thyroxine

Treatments, therapies and supportive options

5

Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.

Surgery

1

Excision

Medical therapy

1

ExcisionWeakly in Favour(Low Evidence)

Alternative and complementary therapies

1

Black Walnut (Juglans Nigra)No Recommendation(Low Evidence)

Vitamins and minerals

1

Selenium SupplementationNo Recommendation(Very Low Evidence)

Minerals

1

Selenium SupplementationNo Recommendation(Very Low Evidence)

Linked diagnostic tests and investigations

2

These are pulled from both EH diagnostic-test link tables, including the older large test-link table.

Biological and test markers

2

This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.

Often increased

1

Thyroglobulin (Tg)Reference range exampleInfant (0 - 1y), Female: 0.4–5.6 ng/mL; Infant (0 - 1y), Male: 0.5–5.6 ng/mLLinked diagnostic tests1Thyroglobulin (Tg) Concentration

Often decreased

1

Functional Residual CapacityReference range exampleAdult ( > 16y): 2,500–3,600 mLLinked diagnostic tests1Functional Residual Capacity

Other associated markers

0

No markers in this group.

Introduction / full article

ID 98

Efficacy of Alternative and Other Treatments According to GRADE* Ranking:

Selenium Supplement [1, 2, 3, 4, 5, 6, 7, 8, 9, 10]:

Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present. IMPORTANT: Selenium is toxic in high doses. Massive overdoses can cause kidney failure, breathing difficulty and death. Selenium should only be taken at healthy levels which the body is able to tolerate.

Recommendation: No recommendation (Available evidene does not support claims that selenium helps to prevent or treat any thyroid conditions)

Grade of Evidence: very low quality of evidence

Black Walnut (Juglans Nigra):

Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.

Recommendation: no recommendation (Available evidence does not support claims that Black Walnut helps to treat goiter)

Grade of Evidence: low quality of evidence

* www.gradeworkinggroup.org

Summary References

Treatment:

1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009

2. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/selenium?sitearea=ETO

3. http://www.cancer.gov/Templates/doc.aspx?viewid=ED8AD8E8-6AE5-458D-8091-393F4CB73F0D

4. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-selenium.html

5. http://www.ncbi.nlm.nih.gov/pubmed/9290116

6. http://www.ncbi.nlm.nih.gov/pubmed/9829869

7. http://www.ncbi.nlm.nih.gov/pubmed/10335455

8. http://www.ncbi.nlm.nih.gov/pubmed/2136228

9. http://www.springerlink.com/content/v0r644v4ju5153k2/

10. http://jnci.oxfordjournals.org/cgi/content/full/101/5/283

11. http://www.merck.com/mmpe/sec19/ch282/ch282b.html?qt=euthyroid%20goiter&alt=sh