Everyone Healthy Library
Systemic Lupus Erythematosus
Condition / disease reference page from the Everyone Healthy database.
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Connected health information
Explore this condition in a clear order
Condition overview
Attributes
Commonalityis rare
Linked signs and symptoms
3Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
6Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
13Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Surgery
1Medical therapy
2Lifestyle changes
4Behavioural changes
3Alternative and complementary therapies
1Alternative medicine
1Linked diagnostic tests and investigations
28These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Alpha-1 Antitrypsin (AAT) Concentration
- Cerebrospinal Fluid Protein Electrophoresis
- Creatine Kinase Concentration
- Creatinine Concentration (Blood, Serum Creatinine)
- Eosinophils Count
- erythrocyte Sedimentation Rate (ESR)
- Fibrinopeptide A (FPA) Action Assay
- Gamma-Glutamyltransferase (GGT) Concentration
- haptoglobin (Hp) concentration
- Heamatocrit (Hct)
- Hemoglobin (Hb) Concentration
- Intracranial Prassure Monitoring (CSF Pressure)
- Lymphocyte Immunophenotyping
- Lymphocytes Count
- Monocyte Absolute Count
- Neutrophil Absolute Count
- Platelet Aggregation Test
- Platelet Count
- Potassium Concentration (K, Blood)
- Protein Electrophoresis (Blood, Serum Protein)
- Red Blood Cell (RBC) Count
- Urine Albumin 24hr test
- Urine Haemologlobin (Hb) Concentration
- Urine Leukocyte Esterase Screening
- Urine Red Blood Cell Cast Concentration
- Urine Red Blood Cells Concentration
- Urine White Blood Cell Cast Concentration
- Urine White Blood Cells Test
Biological markers/agents
33This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
22- Albumin (Cerebrospinal Fluid, CSF)Reference range exampleAll: 10–35 mg/dL; All: 56–76 %Linked diagnostic testsCerebrospinal Fluid Albumin Concentration, Cerebrospinal Fluid Protein Electrophoresis
- Alpha-1 Antintrypsin (AAT)Reference range exampleAdult ( > 16y): 90–215 mg/dLLinked diagnostic testsAlpha-1 Antitrypsin (AAT) Concentration
- Alpha-1-Globulin (Blood, Serum)Reference range exampleAll: 0.1–0.3 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- B Cells (CD19 Percentage)Reference range exampleAll: 3–25 %Linked diagnostic testsLymphocyte Immunophenotyping
- Creatinine (Blood)Reference range exampleInfant (0 - 1y): 0.1–0.4 mg/dL; Adult ( > 16y), Female: 0.6–1.2 mg/dLLinked diagnostic testsCreatinine Concentration (Blood, Serum Creatinine)
- Erythrocyte Sedimentation RateReference range exampleAdult ( > 16y), Female: 0–20 mm/Hr; Adult ( > 16y), Male: 0–15 mm/HrLinked diagnostic testserythrocyte Sedimentation Rate (ESR)
- Fibrinopeptide A (FPA)Reference range exampleAdult ( > 16y), Female: 0.7–3.1 mg/mL; Adult ( > 16y), Male: 0.35–2.5 mg/mLLinked diagnostic testsFibrinopeptide A (FPA) Action Assay
- Gamma Globulin (Blood, Serum)Reference range exampleAll: 0.8–1.7 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Gamma-Glutamyltransferase (GGT)Reference range exampleAdult ( > 16y), Female: 6–30 units/L; Adult ( > 16y), Male: 6–38 units/LLinked diagnostic testsGamma-Glutamyltransferase (GGT) Concentration
- haptoglobin (Hp)Reference range example45–200 mg/dLLinked diagnostic testshaptoglobin (Hp) concentration
- IgG (Cerebrospinal Fluid, CSF)Reference range exampleAll: 0–5 mg/dLLinked diagnostic testsCerebrospinal Fluid Protein Electrophoresis
- Intracranial Pressure (Cerebrospinal Fluid Pressure, CSF Pressure)Linked diagnostic testsIntracranial Prassure Monitoring (CSF Pressure)
- MonocytesReference range exampleAdult ( > 16y): 3–7 %; 0.1–0.5 million/mLLinked diagnostic testsDifferential White Blood Cell Count Tests, Monocyte Absolute Count
- Potassium (K, Blood)AbbreviationKReference range exampleInfant (0 - 1y): 4.1–5.3 mEq/L; Child (0 - 16y): 3.4–4.7 mEq/LLinked diagnostic testsPotassium Concentration (K, Blood)
- PrealbuminReference range exampleAll: 2–7 %Linked diagnostic testsCerebrospinal Fluid Protein Electrophoresis
- Urine AlbuminReference range exampleAdult ( > 16y), Female: 30–105 mg/dL; Adult ( > 16y), Male: 10–145 mg/dLLinked diagnostic testsUrine Albumin 24hr test
- Urine Haemoglobin (Hb)Reference range exampleAdult ( > 16y): 0–0.02 mg/dLLinked diagnostic testsUrine Haemologlobin (Hb) Concentration
- Urine Leukocyte EsteraseReference range exampleAll: 0–1 Not PresentLinked diagnostic testsUrine Leukocyte Esterase Screening
- Urine Red Blood Cell CastsReference range exampleAll: 0–0 Not PresentLinked diagnostic testsUrine Red Blood Cell Cast Concentration
- Urine Red Blood CellsReference range exampleAdult ( > 16y): 0–2 /hpfLinked diagnostic testsUrine Red Blood Cells Concentration
- Urine White Blood Cell CastsReference range exampleAll: 0–0 Not PresentLinked diagnostic testsUrine White Blood Cell Cast Concentration
- Urine White Blood CellsReference range exampleAll: 0–5 /hpfLinked diagnostic testsUrine White Blood Cells Test
Often decreased
11- Albumin (Blood)Reference range exampleAdult ( > 16y): 37–52 gm/dL; Infant (0 - 1y): 4.4–5.4 gm/dLLinked diagnostic testsBlood Albumin Concentration, Protein Electrophoresis (Blood
- Beta GlobulinReference range exampleAll: 0.7–1.2 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- Complete Platelet Aggregation in Response to Collagen, Thrombin, RistocetinReference range exampleAll: 0–1 PresentLinked diagnostic testsPlatelet Aggregation Test
- Creatine Kinase (CK)Reference range exampleAdult ( > 16y), Female: 35–150 units/L; Adult ( > 16y), Male: 40–170 units/LLinked diagnostic testsCreatine Kinase Concentration
- EosinophilsReference range exampleAdult ( > 16y): 0–3 %; 0–3 %Linked diagnostic testsDifferential White Blood Cell Count Tests, Eosinophil Differential Of Total WBC
- Hemoglobin (Hb)Reference range exampleFemale: 78–100 gm/dL; Male: 76–100 gm/dLLinked diagnostic testsHemoglobin (Hb) Concentration, Mean Corpuscular Hemoglobin (MCH) Weight Test
- LymphocytesReference range exampleAdult ( > 16y): 25–40 %; 700–3,500 cells/mm3Linked diagnostic testsDifferential White Blood Cell Count Tests, Lymphocytes Count
- PlateletsReference range exampleChild (0 - 16y): 150–450 109/L; Adult ( > 16y): 135–380 109/LLinked diagnostic testsPlatelet Count
- RBC MassReference range exampleFemale: 36–48 %; Male: 42–52 %Linked diagnostic testsHeamatocrit (Hct)
- Red Blood Cells (RBC)Reference range exampleAdult ( > 16y), Female: 3.6–5 106/mm3; Adult ( > 16y), Male: 4.2–5.4 106/mm3Linked diagnostic testsRed Blood Cell (RBC) Count
- Segmented NeutrophilsReference range exampleAdult ( > 16y): 50–62 %; Adult ( > 16y): 2,500–8,000 mm3Linked diagnostic testsDifferential White Blood Cell Count Tests, Neutrophil Absolute Count
Introduction / full article
Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Pau D'Arco (Lapachol, Tabebuia Impetiginosa, Tabebuia Heptaphylla) [1, 2]:
Please note, this treatment has potentially serious side effects. Some of the chemicals in the plant are known to be toxic. High doses are known to cause liver and kidney. Even at low doses, chemicals in the plant may interfere with blood clotting, causing excess bleeding and anaemia. Pau D'Arco should be avoided, especially by pregnant or breastfeeding women.
Recommendation: Strongly against (There is insufficient evidence to support claims that Pau D'arco helps to treat SLE. This, combined with its potentially harmful side effects if taken without supervision from a doctor or pharmacist gives enough reason to avoid this treatment.)
Grade of Evidence: very low quality of evidence
Ultraviolet Blood Irradiation:
Recommendation: strongly in favor (UV blood irradiation has shown to be effective in the treatment of Systemic Lupus Erythematosus)
Grade of Evidence: Moderate quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/pau-d-arco