Everyone Healthy Library
Anaemia of Chronic Renal Failure
Condition / disease reference page from the Everyone Healthy database.
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Connected health information
Explore this condition in a clear order
Linked signs and symptoms
0No related signs or symptoms are listed yet.
Linked drugs / medications
3Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
3Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Linked diagnostic tests and investigations
54These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- 2,3 Diphosphoglycerate (2,3-DPG) Concentration
- Acid Phosphatase Concentration
- amylase concentration
- Anion Gap
- Apolipoprotein A Concentration
- Apolipoprotein B Concentration
- Bleeding Time (Ivy Method)
- Blood pH Test
- Blood Urea Nitrogen Tests
- Blood Uric Acid Concentration Test
- Calcium Concentration (Blood, Total)
- Carbon Dioxide Total Content (TCO2)
- Chloride Concentration (Blood)
- Creatinine Clearance (CrCl)
- Creatinine Concentration (Blood, Serum Creatinine)
- erythrocyte Sedimentation Rate (ESR)
- Erythropoietin (Ep) Concentration
- Fibrin Degradation Products (FDPs, Fibrin Split Products, FSPs, Fibrin Breakdown Products, Fbps)
- Folic Acid (Folate) Concentration
- Glucose, Blood (Post Prandiol Blood Glucose Test, 2 Hour Post Meal Blood Glucose)
- haptoglobin (Hp) concentration
- Lactate Dehydrogenase Concentration
- Lactic Acid Concentration
- Magnesium Concentration (Mg, Blood)
- Mean Corpuscular Hemoglobin (MCH) Weight Test
- Mean Corpuscular Hemoglobin Concentration (MCHC)
- Mean Corpuscular Volume (MCV)
- Oxygen Saturation Test (Arterial Blood, SaO2)
- Partial Pressure of Oxygen (PO2)
- Phosphate Concentration (PO4, Phosphorus)
- Potassium Concentration (K, Blood)
- Protein Electrophoresis (Blood, Serum Protein)
- Protein S Concentration
- Red Blood Cell (RBC) Count
- Renin Assay
- Reticulocyte Absolute Count
- Sodium Concentration (Na, Blood)
- Sweat Testing
- Thyroxine (Total T4) Concentration
- Triglyceride (TGs) Concentration
- Triiodothyronine (Free T3) Concentration
- Triiodothyronine (Total T3) Concentration
- Triiodothyronine Uptake Test
- Urine Amino Acid Concentration
- Urine Chloride Concentration
- Urine Estriol (E3) Concentration
- Urine Fatty Cast Concentration
- Urine glucose concentration
- Urine Granular Cast Concentration
- Urine Hyaline Cast Concentration
- Urine Lysozyme Concentration
- Urine Potassium (K) Concentration
- Urine Sodium Quantitative (24hr)
- Vitamin B12 (VB12) Concentration
Biological markers/agents
84This visual map shows biological markers/agents reported as increased or decreased with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
65- 1 Methylhistidine (Urine)Reference range exampleChild (0 - 16y): 450–3,200 µmol/L; Adult ( > 16y): 700–8,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- 2,3 Diphosphoglycerate (2,3-DPG)Reference range exampleAdult ( > 16y): 10.5–14 µmol/gLinked diagnostic tests2, 3 Diphosphoglycerate (2
- 3 Methylhistidine (Urine)Reference range exampleChild (0 - 16y): 420–1,400 µmol/L; Adult ( > 16y): 650–3,300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Acid PhosphataseReference range exampleChild (0 - 16y), Male: 8.7–12.5 units/L; Adult ( > 16y), Male: 2.2–10.4 units/LLinked diagnostic testsAcid Phosphatase Concentration
- Alanine (Urine)Reference range exampleAdult ( > 16y): 1,500–7,000 µmol/L; Child (< 10y): 600–2,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alpha Amino N Buryric Acid (Urine)Reference range exampleAdult ( > 16y): 0–350 µmol/L; Child (< 10y): 80–300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alpha Aminoadipic Acid (Urine)Reference range exampleAdult ( > 16y): 0–1,700 µmol/L; Child (< 10y): 240–800 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Alpha-2-Globulin (Blood, Serum)Reference range exampleAll: 0.6–1 gm/dLLinked diagnostic testsProtein Electrophoresis (Blood, Serum Protein)
- AmylaseReference range exampleAdult ( > 16y): 25–125 units/LLinked diagnostic testsamylase concentration
- Anion Gap (Excluding Potassium)Reference range exampleAll: 12–20 mEq/L; All: 8–16 mEq/LLinked diagnostic testsAnion Gap
- Anion Gap (Including Potassium)Reference range exampleAll: 12–20 mEq/LLinked diagnostic testsAnion Gap
- Apolipoprotein B (Apo B)Reference range exampleAdult ( > 16y), Female: 47–115 mg/dL; Adult ( > 16y), Male: 52–120 mg/dLLinked diagnostic testsApolipoprotein B Concentration
- Arginine (Urine)Reference range exampleChild (0 - 16y): 120–260 µmol/L; Adult ( > 16y): 140–650 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Asparagine (Urine)Reference range exampleChild (0 - 16y): 160–420 µmol/L; Adult ( > 16y): 350–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Aspartic Acid (Urine)Reference range exampleChild (0 - 16y): 110–270 µmol/L; Adult ( > 16y): 150–900 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Blood Urea NitrogenReference range exampleAdult ( > 16y): 6–18 mg/dL; Child (< 10y): 5–15 mg/dLLinked diagnostic testsBlood Urea Nitrogen Tests
- Carnosine (Urine)Reference range exampleChild (0 - 16y): 350–2,500 µmol/L; Adult ( > 16y): 170–1,300 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Chloride (Blood, Cl)Reference range exampleAdult ( > 16y): 97–106 mEq/L; Birth - 2wks: 94–106 mEq/LLinked diagnostic testsChloride Concentration (Blood)
- Chloride (Sweat, Cl)Reference range exampleChild (0 - 16y): 0–50 mEq/LLinked diagnostic testsSweat Testing
- Citrulline (Urine)Reference range exampleChild (0 - 16y): 0–140 µmol/L; Adult ( > 16y): 0–100 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Creatinine (Blood)Reference range exampleInfant (0 - 1y): 0.1–0.4 mg/dL; Adult ( > 16y), Female: 0.6–1.2 mg/dLLinked diagnostic testsCreatinine Concentration (Blood, Serum Creatinine)
- Cystine (Urine)Reference range exampleChild (0 - 16y): 120–540 µmol/L; Adult ( > 16y): 300–1,200 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Erythrocyte Sedimentation RateReference range exampleAdult ( > 16y), Female: 0–20 mm/Hr; Adult ( > 16y), Male: 0–15 mm/HrLinked diagnostic testserythrocyte Sedimentation Rate (ESR)
- Fibrin Split ProductsReference range exampleAll: 0–1 mg/dLLinked diagnostic testsFibrin Degradation Products (FDPs, Fibrin Split Products
- Forced Expiratory Volume At Three Seconds (FEV3)Reference range exampleAll: 95–100 %Linked diagnostic testsSpirometry
- Glucose (Blood)Reference range exampleInfant (0 - 1y): 3–6.1 mmol/L; Adult ( > 16y): 0–6.1 mmol/LLinked diagnostic testsfasting Blood Glucose Test, Glucose Tolerance Test (GTT
- Glutamic Acid (Urine)Reference range exampleChild (0 - 16y): 135–240 µmol/L; Adult ( > 16y): 300–1,100 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Glutamine (Urine)Reference range exampleChild (0 - 16y): 1,600–4,000 µmol/L; Adult ( > 16y): 3,000–10,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Glycine (Urine)Reference range exampleChild (0 - 16y): 2,000–8,500 µmol/L; Adult ( > 16y): 8,000–25,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- haptoglobin (Hp)Reference range example45–200 mg/dLLinked diagnostic testshaptoglobin (Hp) concentration
- Histidine (Urine)Reference range exampleChild (0 - 16y): 500–7,300 µmol/L; Adult ( > 16y): 5,000–16,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Isoleucine (Urine)Reference range exampleChild (0 - 16y): 40–150 µmol/L; Child (0 - 16y): 100–250 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Lactate Dehydrogenase (LDH)Reference range exampleInfant (0 - 1y): 120–250 units/L; Adult ( > 16y): 100–200 units/LLinked diagnostic testsLactate Dehydrogenase Concentration
- Lactic Acid (Venous Blood)Reference range exampleAll: 0.5–2.2 mEq/LLinked diagnostic testsLactic Acid Concentration
- Lysine (Urine)Reference range exampleChild (0 - 16y): 200–1,500 µmol/L; Adult ( > 16y): 300–3,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Lysozyme (Muramidase, Urine)Reference range exampleAll: 0–4 mg/24hrsLinked diagnostic testsUrine Lysozyme Concentration
- Magnesium (Mg, Blood)Reference range exampleAdult ( > 16y): 1.3–2.6 mEq/L; Birth - 2wks: 1.4–2.2 mEq/LLinked diagnostic testsMagnesium Concentration (Mg, Blood)
- Methionine (Urine)Reference range exampleChild (0 - 16y): 70–220 µmol/L; Adult ( > 16y): 55–320 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Ornithine (Urine)Reference range exampleChild (0 - 16y): 40–165 µmol/L; Adult ( > 16y): 50–800 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Phenylalanine (Urine)Reference range exampleChild (0 - 16y): 200–600 µmol/L; Adult ( > 16y): 400–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Phosphate (PO4, Phosphorus, P)Reference range exampleAdult ( > 16y): 2.5–4.5 mg/dL; Birth - 2wks: 4.3–9.2 mg/dLLinked diagnostic testsPhosphate Concentration (PO4, Phosphorus)
- Phosphoethanolamine (Urine)Reference range exampleChild (0 - 16y): 250–670 µmol/L; Adult ( > 16y): 200–1,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Phosphoserine (Urine)Reference range exampleChild (0 - 16y): 150–350 µmol/L; Child (0 - 16y): 1,000–2,200 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Potassium (K, Blood)AbbreviationKReference range exampleInfant (0 - 1y): 4.1–5.3 mEq/L; Child (0 - 16y): 3.4–4.7 mEq/LLinked diagnostic testsPotassium Concentration (K, Blood)
- Proline (Urine)Reference range exampleChild (0 - 16y): 0–1 Not PresentLinked diagnostic testsUrine Amino Acid Concentration
- ReninReference range exampleAdult ( > 16y): 0.65–3.3 ng/mL; 16y - 18y: 0–4.4 ng/mLLinked diagnostic testsRenin Assay
- Serine (Urine)Reference range exampleChild (0 - 16y): 1,000–2,200 µmol/L; Adult ( > 16y): 2,000–7,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Sodium (Na, Sweat)Reference range exampleChild (0 - 16y): 70–90 mEq/LLinked diagnostic testsSweat Testing
- Taurine (Urine)Reference range exampleChild (0 - 16y): 600–9,800 µmol/L; Adult ( > 16y): 2,700–13,000 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Template Bleeding TimeReference range exampleAdult ( > 16y): 2.5–9 MinutesLinked diagnostic testsBleeding Time (Ivy Method)
- Threonine (Urine)Reference range exampleChild (0 - 16y): 250–1,000 µmol/L; Adult ( > 16y): 900–3,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- TriglyceridesReference range exampleAdult ( > 16y), Female: 32–137 mg/dL; Adult ( > 16y), Male: 35–155 mg/dLLinked diagnostic testsTriglyceride (TG's) Concentration, Triglyceride (TGs) Concentration
- Triiodothyronine Uptake PercentageReference range exampleAll: 25–38 %Linked diagnostic testsTriiodothyronine Uptake Test
- Tyrosine (Urine)Reference range exampleChild (0 - 16y): 300–850 µmol/L; Adult ( > 16y): 400–1,500 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Unrine Granular CastsReference range exampleAdult ( > 16y): 0–0 Not PresentLinked diagnostic testsUrine Granular Cast Concentration
- Uric Acid, BloodReference range exampleAdult ( > 16y), Female: 2.5–7 mg/dL; Adult ( > 16y), Male: 4–8 mg/dLLinked diagnostic testsBlood Uric Acid Concentration Test
- Urine ChlorideReference range exampleInfant (0 - 1y): 2–10 mmol/day; Child (0 - 16y): 15–14 mmol/dayLinked diagnostic testsUrine Chloride Concentration
- Urine Estriol (E3)Reference range exampleAdult ( > 16y), Female: 0–60 µg/24hrs; Adult ( > 16y), Male: 1–11 µg/24hrsLinked diagnostic testsUrine Estriol (E3) Concentration
- Urine Fatty CastReference range exampleAdult ( > 16y): 0–0 PresentLinked diagnostic testsUrine Fatty Cast Concentration
- Urine glucoseReference range example0–2.5; Adult ( > 16y): 0–2.5 mmol/dayLinked diagnostic testsUrine glucose concentration
- Urine Hyaline CastsReference range exampleAdult ( > 16y): 0–2 /lpfLinked diagnostic testsUrine Hyaline Cast Concentration
- Urine Potassium (K)Reference range exampleAdult ( > 16y): 25–100 mmol/dayLinked diagnostic testsUrine Potassium (K) Concentration
- Urine SodiumReference range exampleChild (0 - 16y): 41–115 mmol/day; Adult ( > 16y): 40–220 mmol/dayLinked diagnostic testsUrine Sodium Quantitative (24hr)
- Valine (Urine)Reference range exampleChild (0 - 16y): 200–400 µmol/L; Adult ( > 16y): 200–750 µmol/LLinked diagnostic testsUrine Amino Acid Concentration
- Vitamin B12 (VB12)Reference range exampleAdult ( > 16y): 130–670 pmol/LLinked diagnostic testsVitamin B12 (VB12) Concentration
Often decreased
19- Albumin (Blood)Reference range exampleAdult ( > 16y): 37–52 gm/dL; Infant (0 - 1y): 4.4–5.4 gm/dLLinked diagnostic testsBlood Albumin Concentration, Protein Electrophoresis (Blood
- Apolipoprotein A (Apo A)Reference range exampleAdult ( > 16y), Female: 85–170 mg/dL; Adult ( > 16y), Male: 77–155 mg/dLLinked diagnostic testsApolipoprotein A Concentration
- Blood pHReference range exampleAll: 7.35–7.45Linked diagnostic testsBlood pH Test
- Calcium (Blood, Total)Reference range exampleAdult ( > 16y): 8.5–10.4 mg/dL; Birth - 2wks: 7.6–10.3 mg/dLLinked diagnostic testsCalcium Concentration (Blood, Total)
- Carbon Dioxide Total Content (TCO2)Reference range exampleInfant (0 - 1y): 20–27 mEq/L; Newborn (0 - 1month): 13–21 mEq/LLinked diagnostic testsCarbon Dioxide Total Content (TCO2)
- Creatinine Clearance RateReference range exampleAdult ( > 16y), Female: 87–110 ml/minute; Adult ( > 16y), Male: 100–140 ml/minuteLinked diagnostic testsCreatinine Clearance (CrCl)
- Erythropoietin (Ep)Reference range exampleAdult ( > 16y): 6–36 units/LLinked diagnostic testsErythropoietin (Ep) Concentration
- Folic Acid (Folate)Reference range exampleInfant (0 - 1y): 14–51 ng/mL; Child (0 - 16y): 5–21 ng/mLLinked diagnostic testsFolic Acid (Folate) Concentration
- Hemoglobin (Hb)Reference range exampleFemale: 78–100 gm/dL; Male: 76–100 gm/dLLinked diagnostic testsHemoglobin (Hb) Concentration, Mean Corpuscular Hemoglobin (MCH) Weight Test
- Oxygen Saturation (Arterial Blood, SaO2)Reference range exampleChild (0 - 16y): 95–100 %; Newborn (0 - 1month): 40–90 %Linked diagnostic testsOxygen Saturation Test (Arterial Blood, SaO2)
- Partial Pressure of Arterial Oxygen (PaO2)Reference range exampleChild (0 - 16y): 80–100 mm Hg; Newborn (0 - 1month): 60–70 mm HgLinked diagnostic testsPartial Pressure of Oxygen (PO2)
- Protein SReference range exampleAdult ( > 16y), Female: 50–120 %; Adult ( > 16y), Male: 55–120 %Linked diagnostic testsProtein S Concentration
- Red Blood Cell (RBC) VolumeReference range example76–100 fLLinked diagnostic testsMean Corpuscular Volume (MCV)
- Red Blood Cells (RBC)Reference range exampleAdult ( > 16y), Female: 3.6–5 106/mm3; Adult ( > 16y), Male: 4.2–5.4 106/mm3Linked diagnostic testsRed Blood Cell (RBC) Count
- ReticulocytesReference range exampleAdult ( > 16y): 24–83 109/L; 0.5–1.5 %Linked diagnostic testsReticulocyte Absolute Count, Reticulocyte Count Percent Total RBC
- Sodium (Na, Blood)Reference range exampleInfant (0 - 1y): 134–150 mEq/L; Child (0 - 16y): 136–145 mEq/LLinked diagnostic testsSodium Concentration (Na, Blood)
- Thyroxine (Total T4)Reference range exampleAdult ( > 16y), Female: 6–12 µg/dL; Adult ( > 16y), Male: 5–12 µg/dLLinked diagnostic testsThyroxine (Total T4) Concentration
- Triiodothyronine (Free T3)Reference range example2.7–4.9 pg/mLLinked diagnostic testsTriiodothyronine (Free T3) Concentration
- Triiodothyronine (Total T3)Reference range exampleInfant (0 - 1y): 1.1–2.43 ng/mL; Adult ( > 16y): 1–2.1 ng/mLLinked diagnostic testsTriiodothyronine (Total T3) Concentration
Introduction / full article
Anaemia of Chronic Renal Failure
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Molybdenum (Mo, Sodium Molybdate) [1, 5, 6, 7, 8, 9]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (There is insufficient evidence to support claims that Molybdenum has any affect on the treatment of anaemia)
Grade of Evidence: very low quality of evidence
Chlorella (Green Algae, Chlorella Pyrenoidosa) [1, 2, 3, 4]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (There is insufficient evidence to support claims that Chlorella helps to treat anemia in any way)
Grade of Evidence: very low quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. Nakano, S et al. “Maternal-fetal distribution and transfer of dioxins in pregnant women in Japan, and attempts to reduce maternal transfer with Chlorella (Chlorella pyrenoidosa) supplements...” Chemosphere 2005 Dec; 61(9): 1244–55.
3. http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=11347287&dopt=Abstract
4. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/chlorella
5. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/molybdenum
6. http://lpi.oregonstate.edu/infocenter/minerals/molybdenum/
7. Hassouneh B, Islam M, Nagel T, Pan Q, Merajver SD, Teknos TN. Tetrathiomolybdate promotes tumor necrosis and prevents distant metastases by suppressing angiogenesis in head and neck cancer. Mol Cancer Ther. 2007;6:1039-1045.
8. Cassileth B. The Alternative Medicine Handbook: The Complete Reference Guide to Alternative and Complementary Therapies. New York, NY: W.W. Norton; 1998.
9. Nakadaira H, Endoh K, Yamamoto M, Katoh K. Distribution of selenium and molybdenum and cancer mortality in Niigata, Japan. Arch Environ Health. 1995;50:374-380.